5-bromo-2-(4-isopropyl-phenyl)-7-methoxy-1-(2-methoxy-ethyl)-1H-benzoimidazole

Base Information

Chemical Name:5-bromo-2-(4-isopropyl-phenyl)-7-methoxy-1-(2-methoxy-ethyl)-1H-benzoimidazole
CAS No.:860466-28-0
Molecular Formula:C₂₀H₂₃BrN₂O₂
Molecular Weight:403.319
Hs Code.:

Synonyms:5-bromo-2-(4-isopropyl-phenyl)-7-methoxy-1-(2-methoxy-ethyl)-1H-benzoimidazole

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Chemical Property of 5-bromo-2-(4-isopropyl-phenyl)-7-methoxy-1-(2-methoxy-ethyl)-1H-benzoimidazole

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Technology Process of 5-bromo-2-(4-isopropyl-phenyl)-7-methoxy-1-(2-methoxy-ethyl)-1H-benzoimidazole

There total 2 articles about 5-bromo-2-(4-isopropyl-phenyl)-7-methoxy-1-(2-methoxy-ethyl)-1H-benzoimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 860466-33-7
N-[5-bromo-3-methoxy-2-(2-methoxy-ethylamino)-phenyl]-4-isopropyl-benzamide

: 860466-28-0
5-bromo-2-(4-isopropyl-phenyl)-7-methoxy-1-(2-methoxy-ethyl)-1H-benzoimidazole

Guidance literature:: N-[5-bromo-3-methoxy-2-(2-methoxy-ethylamino)-phenyl]-4-isopropyl-benzamide; With acetic acid; In water; at 100 ℃; for 2h;

With sodium hydroxide; In water; Product distribution / selectivity;

Reference yield:

: 6482-24-2
2-Bromoethyl methyl ether

: 860466-28-0
5-bromo-2-(4-isopropyl-phenyl)-7-methoxy-1-(2-methoxy-ethyl)-1H-benzoimidazole

Guidance literature:: C₁₇H₁₇BrN₂O; With sodium hydride; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 1h;

2-Bromoethyl methyl ether; In DMF (N,N-dimethyl-formamide); at 60 ℃; for 6h; Product distribution / selectivity;

Reference yield: 32.0%

: 860466-28-0
5-bromo-2-(4-isopropyl-phenyl)-7-methoxy-1-(2-methoxy-ethyl)-1H-benzoimidazole

: 832114-00-8
3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoxazole

: 1613695-92-3
C₂₅H₂₉N₃O₃

Guidance literature:: With [1,1'-bis(diphenylphosphino)ferrocene]dichloropalladium(II); sodium hydrogencarbonate; In 1,2-dimethoxyethane; at 100 ℃; for 24h; Inert atmosphere;
DOI:10.1021/ja412434f