methyl 4-{[(1S,4aS,8aS)-1,4a-dimethyl-2-methylene-5-oxodecahydronaphthalen-1-yl]methyl}-3-hydroxy-5-methoxybenzoate

Base Information

Chemical Name:methyl 4-{[(1S,4aS,8aS)-1,4a-dimethyl-2-methylene-5-oxodecahydronaphthalen-1-yl]methyl}-3-hydroxy-5-methoxybenzoate
CAS No.:1312022-51-7
Molecular Formula:C₂₃H₃₀O₅
Molecular Weight:386.488
Hs Code.:

Synonyms:methyl 4-{[(1S,4aS,8aS)-1,4a-dimethyl-2-methylene-5-oxodecahydronaphthalen-1-yl]methyl}-3-hydroxy-5-methoxybenzoate

Suppliers and Price of methyl 4-{[(1S,4aS,8aS)-1,4a-dimethyl-2-methylene-5-oxodecahydronaphthalen-1-yl]methyl}-3-hydroxy-5-methoxybenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 4-{[(1S,4aS,8aS)-1,4a-dimethyl-2-methylene-5-oxodecahydronaphthalen-1-yl]methyl}-3-hydroxy-5-methoxybenzoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 4-{[(1S,4aS,8aS)-1,4a-dimethyl-2-methylene-5-oxodecahydronaphthalen-1-yl]methyl}-3-hydroxy-5-methoxybenzoate

There total 1 articles about methyl 4-{[(1S,4aS,8aS)-1,4a-dimethyl-2-methylene-5-oxodecahydronaphthalen-1-yl]methyl}-3-hydroxy-5-methoxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 1312022-50-6
methyl 4-{[(4a'S,5'S,8a'S)-5',8'-dimethyl-6-methyleneoctahydro-2'H-spiro[[1,3]dioxolane-2,1'-naphthalen]-5-yl]methyl}-3-hydroxy-5-methoxybenzoate

: 1312022-51-7
methyl 4-{[(1S,4aS,8aS)-1,4a-dimethyl-2-methylene-5-oxodecahydronaphthalen-1-yl]methyl}-3-hydroxy-5-methoxybenzoate

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; water; at 20 ℃; for 24h;
DOI:10.1002/ejoc.201100173

Reference yield: 96.0%

: 1312022-51-7
methyl 4-{[(1S,4aS,8aS)-1,4a-dimethyl-2-methylene-5-oxodecahydronaphthalen-1-yl]methyl}-3-hydroxy-5-methoxybenzoate

: 1312022-52-8
methyl 3-hydroxy-5-methoxy-4-{[(1R,2S,4aS,8aS)-1,2,4a-trimethyl-5-oxodecahydronaphthalen-1-yl]methyl}benzoate

Guidance literature:: With palladium 10% on activated carbon; hydrogen; triethylamine; In methanol; at 20 ℃; for 24h; under 760.051 Torr;
DOI:10.1002/ejoc.201100173

Reference yield:

: 1312022-51-7
methyl 4-{[(1S,4aS,8aS)-1,4a-dimethyl-2-methylene-5-oxodecahydronaphthalen-1-yl]methyl}-3-hydroxy-5-methoxybenzoate

: 1312022-53-9
methyl 3-hydroxy-5-methoxy-4-{[(1R,2S,4aS,8aS)-1,2,4a-trimethyl-5-methylenedecahydronaphthalen-1-yl]methyl}benzoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: palladium 10% on activated carbon; hydrogen; triethylamine / methanol / 24 h / 20 °C / 760.05 Torr

2.1: potassium tert-butylate / benzene / 2 h / Inert atmosphere; Reflux

2.2: 2 h / Inert atmosphere; Reflux

With palladium 10% on activated carbon; potassium tert-butylate; hydrogen; triethylamine; In methanol; benzene; 2.1: Wittig methylenation / 2.2: Wittig methylenation;
DOI:10.1002/ejoc.201100173