Ergosta-5,24(28),25-trien-3-ol

Base Information

• Chemical Name: Ergosta-5,24(28),25-trien-3-ol
• CAS No.: 102607-76-1
• Molecular Formula: C₂₈H₄₄O
• Molecular Weight: 396.657
• DSSTox Substance ID: DTXSID50907914
• Metabolomics Workbench ID: 34858
• Mol file: 102607-76-1.mol

Synonyms:5,24,25-EGT;ergosta-5,24(28),25-trien-3-ol

Chemical Property of Ergosta-5,24(28),25-trien-3-ol

Chemical Property:

• Vapor Pressure: 4.27E-12mmHg at 25°C
• Boiling Point: 500.1°Cat760mmHg
• Flash Point: 215.9°C
• PSA: 20.23000
• Density: 0.99g/cm³
• LogP: 7.47490
• XLogP3: 8.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 5
• Exact Mass: 396.339216023
• Heavy Atom Count: 29
• Complexity: 701

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(CCC(=C)C(=C)C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C
• Isomeric SMILES: C[C@H](CCC(=C)C(=C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C

Technology Process of Ergosta-5,24(28),25-trien-3-ol

There total 2 articles about Ergosta-5,24(28),25-trien-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6β-methoxy-3α,5-cyclo-5α-cholan-24-al (70209-37-9) → Ergosta-5,24(28),25-trien-3β-ol (102607-76-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 2) Collins reagent / 1) Et₂O, overnight

2: 1) n-BuLi, 2) p-TsOH / 1) Et₂O, hexane, 5 d, 2) 20percent aq. dioxane

With n-butyllithium; Collins oxidation agent; toluene-4-sulfonic acid;

DOI:10.1016/0039-128X(85)90009-1

Reference yield:

methyl-triphenylphosphonium iodide (2065-66-9) + 6β-methoxy-3α,5-cyclo-cholest-25(26)-en-24-one → Ergosta-5,24(28),25-trien-3β-ol (102607-76-1)

Guidance literature:

With n-butyllithium; toluene-4-sulfonic acid; Yield given. Multistep reaction; 1) Et₂O, hexane, 5 d, 2) 20percent aq. dioxane;

DOI:10.1016/0039-128X(85)90009-1

upstream raw materials:

methyl-triphenylphosphonium iodide

6β-methoxy-3α,5-cyclo-5α-cholan-24-al

Refernces