Technology Process of C17H19BrN6O2
There total 7 articles about C17H19BrN6O2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
boron tribromide;
In
dichloromethane;
for 18h;
Cooling with ice;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: acetonitrile / 3 h / 80 °C
2: hydrogenchloride / methanol / 2 h
3: N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; 1,1'-carbonyldiimidazole / tetrahydrofuran / 1 h
4: boron tribromide / dichloromethane / 18 h / Cooling with ice
With
hydrogenchloride; boron tribromide; N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; 1,1'-carbonyldiimidazole;
In
tetrahydrofuran; methanol; dichloromethane; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: N-ethyl-N,N-diisopropylamine / acetonitrile / Reflux
2: dmap; triethylamine / tetrahydrofuran / 2 h / Reflux
3: potassium phosphate; tetrakis(triphenylphosphine) palladium(0); XPhos / 1,4-dioxane; water / 2 h / 80 °C / Inert atmosphere
4: acetonitrile / 3 h / 80 °C
5: hydrogenchloride / methanol / 2 h
6: N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; 1,1'-carbonyldiimidazole / tetrahydrofuran / 1 h
7: boron tribromide / dichloromethane / 18 h / Cooling with ice
With
hydrogenchloride; dmap; potassium phosphate; tetrakis(triphenylphosphine) palladium(0); boron tribromide; triethylamine; N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; 1,1'-carbonyldiimidazole; XPhos;
In
tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; water; acetonitrile;
3: |Suzuki Coupling;
