(-)-(R)-N-<(Furan-2-yl)methyl>-N-(2-hyydroxy-1-phenylethyl)-3-methylbut-2-enamid

Base Information

• Chemical Name: (-)-(R)-N-<(Furan-2-yl)methyl>-N-(2-hyydroxy-1-phenylethyl)-3-methylbut-2-enamid
• CAS No.: 77704-70-2
• Molecular Formula: C₁₈H₂₁NO₃
• Molecular Weight: 299.37

Synonyms:(-)-(R)-N-<(Furan-2-yl)methyl>-N-(2-hyydroxy-1-phenylethyl)-3-methylbut-2-enamid

Chemical Property of (-)-(R)-N-<(Furan-2-yl)methyl>-N-(2-hyydroxy-1-phenylethyl)-3-methylbut-2-enamid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (-)-(R)-N-<(Furan-2-yl)methyl>-N-(2-hyydroxy-1-phenylethyl)-3-methylbut-2-enamid

There total 12 articles about (-)-(R)-N-<(Furan-2-yl)methyl>-N-(2-hyydroxy-1-phenylethyl)-3-methylbut-2-enamid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

(-)-(R)-<2--N-(3-methylbut-2-enoyl)amino>-2-phenylethyl>-3-methyl-but-2-enoat (132168-56-0) → (-)-(R)-N-<(Furan-2-yl)methyl>-N-(2-hyydroxy-1-phenylethyl)-3-methylbut-2-enamid (77704-70-2)

Guidance literature:

With water; potassium carbonate; In methanol; dichloromethane; for 2.5h; Heating;

DOI:10.1002/hlca.19900730816

Reference yield:

(-)-(R)-2<<(Furan-2-yl)methyl>amino>-2-phenylethanol (132168-60-6) → (-)-(R)-N-<(Furan-2-yl)methyl>-N-(2-hyydroxy-1-phenylethyl)-3-methylbut-2-enamid (77704-70-2)

Guidance literature:

Multi-step reaction with 3 steps

1: pyridine / tetrahydrofuran / 2 h

2: pyridine / tetrahydrofuran / 16 h

3: 139 g / aq. HCl / tetrahydrofuran

With pyridine; hydrogenchloride; In tetrahydrofuran;

DOI:10.1039/b201987f

Reference yield:

D-2-phenylglycinol (56613-80-0) → (-)-(R)-N-<(Furan-2-yl)methyl>-N-(2-hyydroxy-1-phenylethyl)-3-methylbut-2-enamid (77704-70-2)

Guidance literature:

Multi-step reaction with 5 steps

1: toluene / Heating

2: NaBH₄ / propan-2-ol

3: pyridine / tetrahydrofuran

5: aq. HCl

With pyridine; hydrogenchloride; sodium tetrahydroborate; In tetrahydrofuran; isopropyl alcohol; toluene; 1: Condensation / 2: Reduction / 3: Etherification / 4: Acylation / 5: Hydrolysis;

DOI:10.1039/b003757p

upstream raw materials:

(-)-(R)-<2--N-(3-methylbut-2-enoyl)amino>-2-phenylethyl>-3-methyl-but-2-enoat

furfural

3,3-Dimethylacryloyl chloride

D-2-phenylglycinol

Downstream raw materials:

(1R,5S,7S)-3-[(1R)-2-chloro-1-phenylethyl]-6,6-dimethyl-10-oxa-3-azatricyclo[5.2.1.0^1,5]dec-8-en-4-one

(+)-(1R,2S,4R,5S)-1-(tert-butyldiphenylsilyloxy)-1-formyl-3,3-dimethyl-7-oxabicyclo[2.2.1]heptane-2-carboxylic acid ethyl ester

(+)-(1R,2S,4R,5S)-5-(tert-butyldiphenylsilyloxy)-1-hydroxymethyl-3,3-dimethyl-7-oxabicyclo[2.2.1]heptane-2-carboxylic acid ethyl ester

(+)-(1R,2S,4R,5S)-1-(tert-butyldimethylsilyloxymethyl)-5-(tert-butyldiphenylsilyloxy)-3,3-dimethyl-7-oxabicyclo[2.2.1]heptane-2-carboxylic acid ethyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 77704-70-2 (-)-(R)-N-<(Furan-2-yl)methyl>-N-(2-hyydroxy-1-phenylethyl)-3-methylbut-2-enamid

Send

Send

Metric Ton KG G Pound L ML

Send

Send