methyl 5-((4-(8-azidooctyloxy)phenyl)diazenyl)-2-hydroxybenzoate

Base Information

• Chemical Name: methyl 5-((4-(8-azidooctyloxy)phenyl)diazenyl)-2-hydroxybenzoate
• CAS No.: 1392196-84-7
• Molecular Formula: C₂₂H₂₇N₅O₄
• Molecular Weight: 425.487
• Mol file: 1392196-84-7.mol

Synonyms:methyl 5-((4-(8-azidooctyloxy)phenyl)diazenyl)-2-hydroxybenzoate

Chemical Property of methyl 5-((4-(8-azidooctyloxy)phenyl)diazenyl)-2-hydroxybenzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 5-((4-(8-azidooctyloxy)phenyl)diazenyl)-2-hydroxybenzoate

There total 5 articles about methyl 5-((4-(8-azidooctyloxy)phenyl)diazenyl)-2-hydroxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

5-((4-(8-azidooctyloxy)phenyl)diazenyl)-2-hydroxybenzoic acid (1392196-83-6) + dimethyl sulfate (77-78-1) → methyl 5-((4-(8-azidooctyloxy)phenyl)diazenyl)-2-hydroxybenzoate (1392196-84-7)

Guidance literature:

With potassium carbonate; In acetone; at 20 ℃; for 0.333333h; Reflux;

DOI:10.1021/ml300086c

Reference yield:

1-((8-bromooctyl)oxy)-4-nitrobenzene (88138-53-8) → methyl 5-((4-(8-azidooctyloxy)phenyl)diazenyl)-2-hydroxybenzoate (1392196-84-7)

Guidance literature:

Multi-step reaction with 4 steps

1.1: 10% Pd/C; hydrogen / ethanol / 3 h / 2068.65 Torr

2.1: hydrogenchloride; sodium nitrite / water / 0.33 h / 0 °C

2.2: 0.5 h / 0 - 20 °C / pH 12 - 14

3.1: sodium azide / dimethyl sulfoxide / 48 h / 20 °C

4.1: potassium carbonate / acetone / 0.33 h / 20 °C / Reflux

With hydrogenchloride; sodium azide; 10% Pd/C; hydrogen; potassium carbonate; sodium nitrite; In ethanol; water; dimethyl sulfoxide; acetone;

DOI:10.1021/ml300086c

Reference yield:

4-(8-bromooctyloxy)aniline (1392196-81-4) → methyl 5-((4-(8-azidooctyloxy)phenyl)diazenyl)-2-hydroxybenzoate (1392196-84-7)

Guidance literature:

Multi-step reaction with 3 steps

1.1: hydrogenchloride; sodium nitrite / water / 0.33 h / 0 °C

1.2: 0.5 h / 0 - 20 °C / pH 12 - 14

2.1: sodium azide / dimethyl sulfoxide / 48 h / 20 °C

3.1: potassium carbonate / acetone / 0.33 h / 20 °C / Reflux

With hydrogenchloride; sodium azide; potassium carbonate; sodium nitrite; In water; dimethyl sulfoxide; acetone;

DOI:10.1021/ml300086c

upstream raw materials:

1,8-dibromooctane

1-((8-bromooctyl)oxy)-4-nitrobenzene

5-((4-(8-azidooctyloxy)phenyl)diazenyl)-2-hydroxybenzoic acid

dimethyl sulfate