ethyl 4-{4-[5-(2-carbomethoxyphenyl)-1,3,4-oxadiazol-2-yl]benzyloxy}-2-methyl-quinoline-6-carboxylate

Base Information

Chemical Name:ethyl 4-{4-[5-(2-carbomethoxyphenyl)-1,3,4-oxadiazol-2-yl]benzyloxy}-2-methyl-quinoline-6-carboxylate
CAS No.:593287-18-4
Molecular Formula:C₃₀H₂₅N₃O₆
Molecular Weight:523.545
Hs Code.:

Synonyms:ethyl 4-{4-[5-(2-carbomethoxyphenyl)-1,3,4-oxadiazol-2-yl]benzyloxy}-2-methyl-quinoline-6-carboxylate

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Chemical Property of ethyl 4-{4-[5-(2-carbomethoxyphenyl)-1,3,4-oxadiazol-2-yl]benzyloxy}-2-methyl-quinoline-6-carboxylate

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Technology Process of ethyl 4-{4-[5-(2-carbomethoxyphenyl)-1,3,4-oxadiazol-2-yl]benzyloxy}-2-methyl-quinoline-6-carboxylate

There total 6 articles about ethyl 4-{4-[5-(2-carbomethoxyphenyl)-1,3,4-oxadiazol-2-yl]benzyloxy}-2-methyl-quinoline-6-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 593287-13-9,300590-94-7
ethyl 2-methyl-4-oxo-1,4-dihydroquinoline-6-carboxylate

: 593287-06-0
methyl 2-[5-[4-(bromomethyl)phenyl]-1,3,4-oxadiazol-2-yl]benzoate

: 593287-18-4
ethyl 4-{4-[5-(2-carbomethoxyphenyl)-1,3,4-oxadiazol-2-yl]benzyloxy}-2-methyl-quinoline-6-carboxylate

Guidance literature:: With potassium carbonate; In acetonitrile; for 4h; Heating;

Reference yield:

: 4376-18-5
Monomethyl phthalate

: 593287-18-4
ethyl 4-{4-[5-(2-carbomethoxyphenyl)-1,3,4-oxadiazol-2-yl]benzyloxy}-2-methyl-quinoline-6-carboxylate

Guidance literature:: Multi-step reaction with 4 steps

1: SOCl₂ / 1 h / Heating

2: 5.47 g / pyridine / 1 h / 100 °C

3: NBS; benzoyl peroxide / CCl₄ / 4 h / Heating

4: 70 percent / K₂CO₃ / acetonitrile / 4 h / Heating

With pyridine; N-Bromosuccinimide; thionyl chloride; potassium carbonate; dibenzoyl peroxide; In tetrachloromethane; acetonitrile;

Reference yield:

: 4397-55-1
phthalic monoacid monomethyl ester chloride

: 593287-18-4
ethyl 4-{4-[5-(2-carbomethoxyphenyl)-1,3,4-oxadiazol-2-yl]benzyloxy}-2-methyl-quinoline-6-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: 5.47 g / pyridine / 1 h / 100 °C

2: NBS; benzoyl peroxide / CCl₄ / 4 h / Heating

3: 70 percent / K₂CO₃ / acetonitrile / 4 h / Heating

With pyridine; N-Bromosuccinimide; potassium carbonate; dibenzoyl peroxide; In tetrachloromethane; acetonitrile;