5-((3,4-Dimethylphenyl)methyl)-2,4-thiazolidinedione

Base Information

Chemical Name:5-((3,4-Dimethylphenyl)methyl)-2,4-thiazolidinedione
CAS No.:79525-06-7
Molecular Formula:C12H13NO2S
Molecular Weight:235.307
Hs Code.:
DSSTox Substance ID:DTXSID501000571

Synonyms:BRN 5527331;79525-06-7;5-((3,4-Dimethylphenyl)methyl)-2,4-thiazolidinedione;2,4-Thiazolidinedione, 5-((3,4-dimethylphenyl)methyl)-;SCHEMBL8913287;DTXSID501000571;LS-151320;5-[(3,4-Dimethylphenyl)methyl]-4-hydroxy-1,3-thiazol-2(5H)-one

Suppliers and Price of 5-((3,4-Dimethylphenyl)methyl)-2,4-thiazolidinedione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-((3,4-Dimethylphenyl)methyl)-2,4-thiazolidinedione

Chemical Property:

Vapor Pressure:3.06E-07mmHg at 25°C
Boiling Point:419.3°Cat760mmHg
Flash Point:207.4°C
Density:1.251g/cm³
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:235.06669983
Heavy Atom Count:16
Complexity:305

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=C(C=C1)CC2C(=O)NC(=O)S2)C

Technology Process of 5-((3,4-Dimethylphenyl)methyl)-2,4-thiazolidinedione

There total 3 articles about 5-((3,4-Dimethylphenyl)methyl)-2,4-thiazolidinedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 95-64-7
4-amino-o-xylene

: 79525-06-7
5-(3,4-dimethylbenzyl)thiazolidine-2,4-dione

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) NaNO₂, conc. HCl, 2.) Cu₂O / 1.) H₂O, acetone, 5 deg C, 15 min, 2.) H₂O, acetone, 5 -> 35 deg C

2: 60.3 percent / AcONa / 2-methoxy-ethanol / 16 h / 100 °C

3: 1N HCl / ethanol / 10 h / Heating

With copper(I) oxide; hydrogenchloride; sodium acetate; sodium nitrite; In ethanol; 2-methoxy-ethanol;
DOI:10.1248/cpb.31.560

Reference yield:

: 86733-93-9
5-(3,4-Dimethyl-benzyl)-2-imino-thiazolidin-4-one

: 79525-06-7
5-(3,4-dimethylbenzyl)thiazolidine-2,4-dione

Guidance literature:: With hydrogenchloride; In ethanol; for 10h; Yield given; Heating;
DOI:10.1248/cpb.31.560

Reference yield:

: 79524-92-8
methyl 2-chloro-3-(3,4-dimethylphenyl)propionate

: 79525-06-7
5-(3,4-dimethylbenzyl)thiazolidine-2,4-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 60.3 percent / AcONa / 2-methoxy-ethanol / 16 h / 100 °C

2: 1N HCl / ethanol / 10 h / Heating

With hydrogenchloride; sodium acetate; In ethanol; 2-methoxy-ethanol;
DOI:10.1248/cpb.31.560