1-Bromo-3-(fluoromethoxy)benzene

Base Information

Chemical Name:1-Bromo-3-(fluoromethoxy)benzene
CAS No.:496052-50-7
Molecular Formula:C₇H₆BrFO
Molecular Weight:205.026
Hs Code.:
European Community (EC) Number:864-604-3

Synonyms:1-bromo-3-(fluoromethoxy)benzene;496052-50-7;4-BROMO-2-FLUOROMETHOXYBENZENE;SCHEMBL542315;EN300-7654178

Suppliers and Price of 1-Bromo-3-(fluoromethoxy)benzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
3-fluoro-5-bromoanisole 97.00%
25G
$ 13300.00

AccelPharmtech
3-fluoro-5-bromoanisole 97.00%
5G
$ 5360.00

AccelPharmtech
3-fluoro-5-bromoanisole 97.00%
1G
$ 3120.00

Total 2 raw suppliers

Chemical Property of 1-Bromo-3-(fluoromethoxy)benzene

Chemical Property:

Boiling Point:214.0±15.0 °C(Predicted)
Density:1.517±0.06 g/cm3(Predicted)
XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:203.95861
Heavy Atom Count:10
Complexity:99.6

Purity/Quality:

98%Min ^*data from raw suppliers

3-fluoro-5-bromoanisole 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC(=C1)Br)OCF

Technology Process of 1-Bromo-3-(fluoromethoxy)benzene

There total 4 articles about 1-Bromo-3-(fluoromethoxy)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 1798-99-8
3-bromophenoxyacetic acid

: 496052-50-7
1-bromo-3-(fluoromethoxy)benzene

Guidance literature:: With 2,6-di-tert-butyl-pyridine; N-fluorobis(benzenesulfon)imide; In acetone; for 3h; Reagent/catalyst; Inert atmosphere; Irradiation;
DOI:10.1002/ejoc.201500038

Reference yield: 67.0%

: 1-((methylsulfinyl)methoxy)-3-bromobenzene

: 496052-50-7
1-bromo-3-(fluoromethoxy)benzene

Guidance literature:: With copper(l) iodide; diethylamino-sulfur trifluoride; In dichloromethane; at 25 ℃; for 18h; Reagent/catalyst; Inert atmosphere;
DOI:10.1021/acs.joc.7b01438

Reference yield:

: 591-20-8
3-Bromophenol

: 496052-50-7
1-bromo-3-(fluoromethoxy)benzene

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 20 °C / Inert atmosphere

2.1: sodium hydroxide; water / methanol / 1 h / 20 °C / Inert atmosphere

2.2: Inert atmosphere

3.1: sodium hydroxide / water / 0.08 h / Inert atmosphere

3.2: 1 h / Inert atmosphere; UV-irradiation

With water; potassium carbonate; sodium hydroxide; In methanol; water; N,N-dimethyl-formamide;
DOI:10.1002/anie.201206352