(S)-2-methyl-propane-2-sulfinic acid 1-(4-nitrophenyl)-meth-(E)-ylideneamide

Base Information

• Chemical Name: (S)-2-methyl-propane-2-sulfinic acid 1-(4-nitrophenyl)-meth-(E)-ylideneamide
• CAS No.: 683226-93-9
• Molecular Formula: C₁₁H₁₄N₂O₃S
• Molecular Weight: 254.31
• Mol file: 683226-93-9.mol

Synonyms:(S)-2-methyl-propane-2-sulfinic acid 1-(4-nitrophenyl)-meth-(E)-ylideneamide

Chemical Property of (S)-2-methyl-propane-2-sulfinic acid 1-(4-nitrophenyl)-meth-(E)-ylideneamide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of (S)-2-methyl-propane-2-sulfinic acid 1-(4-nitrophenyl)-meth-(E)-ylideneamide

There total 1 articles about (S)-2-methyl-propane-2-sulfinic acid 1-(4-nitrophenyl)-meth-(E)-ylideneamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

4-nitrobenzaldehdye (555-16-8) + (S)-2-methylpropane-2-sulfinamide (343338-28-3) → (S)-2-methyl-propane-2-sulfinic acid 1-(4-nitrophenyl)-meth-(E)-ylideneamide (683226-93-9)

Guidance literature:

With copper(II) sulfate; In dichloromethane; for 24h; Inert atmosphere;

DOI:10.1080/00397910802654898

Reference yield: 98.0%

benzyl (tert-butoxycarbonyl)oxycarbamate + (S)-2-methyl-propane-2-sulfinic acid 1-(4-nitrophenyl)-meth-(E)-ylideneamide (683226-93-9) → (SS,2R,3S)-N-tert-butanesulfinyl-O-[(tert-butyloxy)carbonyl]-3-(4-nitrophenyl)isoserine benzyl ester

Guidance literature:

With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃;

DOI:10.1021/jo052298n

Reference yield: 97.0%

3-fluoro-3-(2,2,2-trifluoro-1,1-dihydroxyethyl)-1,3-dihydroindole-2-one + (S)-2-methyl-propane-2-sulfinic acid 1-(4-nitrophenyl)-meth-(E)-ylideneamide (683226-93-9) → C19H20FN3O4S

Guidance literature:

With triethylamine; lithium bromide; In acetonitrile; at 0 ℃; for 0.166667h; diastereoselective reaction;

DOI:10.1039/c6ra27710a

upstream raw materials:

4-nitrobenzaldehdye

(S)-2-methylpropane-2-sulfinamide

Downstream raw materials:

1-[(1,1-dimethylethyl)sulfinyl]-2-(4-nitrophenyl)aziridine