5-Ethoxy-1-((4-methylphenyl)sulfonyl)-2-pyrrolidinone

Base Information

• Chemical Name: 5-Ethoxy-1-((4-methylphenyl)sulfonyl)-2-pyrrolidinone
• CAS No.: 111711-61-6
• Molecular Formula: C13H17 N O4 S
• Molecular Weight: 283.3434
• DSSTox Substance ID: DTXSID70912267
• Nikkaji Number: J423.486C
• Mol file: 111711-61-6.mol

Synonyms:BRN 4755491;5-Ethoxy-1-((4-methylphenyl)sulfonyl)-2-pyrrolidinone;2-Pyrrolidinone, 5-ethoxy-1-((4-methylphenyl)sulfonyl)-;111711-61-6;DTXSID70912267;N-tosyl-5-ethoxy-2-pyrrolidinone;LS-138780;5-Ethoxy-1-[[4-methylphenyl]sulfonyl]pyrrolidin-2-one;5-Ethoxy-1-(4-methylbenzene-1-sulfonyl)pyrrolidin-2-one

Chemical Property of 5-Ethoxy-1-((4-methylphenyl)sulfonyl)-2-pyrrolidinone

Chemical Property:

• Vapor Pressure: 3.91E-07mmHg at 25°C
• Boiling Point: 416.1°Cat760mmHg
• Flash Point: 205.5°C
• Density: 1.31g/cm³
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 283.08782920
• Heavy Atom Count: 19
• Complexity: 420

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC1CCC(=O)N1S(=O)(=O)C2=CC=C(C=C2)C

Technology Process of 5-Ethoxy-1-((4-methylphenyl)sulfonyl)-2-pyrrolidinone

There total 1 articles about 5-Ethoxy-1-((4-methylphenyl)sulfonyl)-2-pyrrolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

5-ethoxy-pyrrolidin-2-one (39662-63-0) + p-toluenesulfonyl chloride (98-59-9) → 5-ethoxy-1-p-toluenesulfonyl-2-pyrrolidinone (111711-61-6)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; hexane; 1.) -78 deg C, 1 h, 2.) warm to room temperature;

DOI:10.1021/jo971192s

Reference yield: 97.0%

5-ethoxy-1-p-toluenesulfonyl-2-pyrrolidinone (111711-61-6) + N-(5-chloropyridin-2-yl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulphonyl]methanesulphonamide (145100-51-2) → Trifluoro-methanesulfonic acid 5-ethoxy-1-(toluene-4-sulfonyl)-4,5-dihydro-1H-pyrrol-2-yl ester (178320-64-4)

Guidance literature:

With potassium hexamethylsilazane; In tetrahydrofuran; at -78 ℃; for 1.5h;

DOI:10.1016/0040-4039(96)01883-7

Reference yield: 60.0%

trifluoromethylsulfonic anhydride (358-23-6) + 5-ethoxy-1-p-toluenesulfonyl-2-pyrrolidinone (111711-61-6) → Trifluoro-methanesulfonic acid 5-ethoxy-1-(toluene-4-sulfonyl)-4,5-dihydro-1H-pyrrol-2-yl ester (178320-64-4)

Guidance literature:

With potassium hexamethylsilazane; In tetrahydrofuran; -78 deg C, 1 h; -78 deg C to room temp.;

DOI:10.1016/0040-4039(96)00612-0

upstream raw materials:

5-ethoxy-pyrrolidin-2-one

p-toluenesulfonyl chloride

Downstream raw materials:

Trifluoro-methanesulfonic acid 5-ethoxy-1-(toluene-4-sulfonyl)-4,5-dihydro-1H-pyrrol-2-yl ester

2-Ethoxy-1-(toluene-4-sulfonyl)-5-vinyl-2,3-dihydro-1H-pyrrole

5-Ethoxy-1-(toluene-4-sulfonyl)-4,5-dihydro-1H-pyrrole-2-carboxylic acid methyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 111711-61-6 5-ethoxy-1-[(4-methylphenyl)sulfonyl]pyrrolidin-2-one

Send

Send

Metric Ton KG G Pound L ML

Send

Send