[1-(2-benzyloxy-biphenyl-3-yl)-ethyl]-bis-(2-benzyloxy-biphenyl-3-ylmethyl)-amine

Base Information

• Chemical Name: [1-(2-benzyloxy-biphenyl-3-yl)-ethyl]-bis-(2-benzyloxy-biphenyl-3-ylmethyl)-amine
• CAS No.: 938435-17-7
• Molecular Formula: C₆₁H₅₃NO₃
• Molecular Weight: 848.097
• Mol file: 938435-17-7.mol

Synonyms:[1-(2-benzyloxy-biphenyl-3-yl)-ethyl]-bis-(2-benzyloxy-biphenyl-3-ylmethyl)-amine

Chemical Property of [1-(2-benzyloxy-biphenyl-3-yl)-ethyl]-bis-(2-benzyloxy-biphenyl-3-ylmethyl)-amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [1-(2-benzyloxy-biphenyl-3-yl)-ethyl]-bis-(2-benzyloxy-biphenyl-3-ylmethyl)-amine

There total 5 articles about [1-(2-benzyloxy-biphenyl-3-yl)-ethyl]-bis-(2-benzyloxy-biphenyl-3-ylmethyl)-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

1-(2-benzyloxybiphenyl-3-yl)-methylbromide (938435-16-6) + 1-(2-benzyloxy-biphenyl-3-yl)-ethylamine; hydrochloride → [1-(2-benzyloxy-biphenyl-3-yl)-ethyl]-bis-(2-benzyloxy-biphenyl-3-ylmethyl)-amine (938435-17-7)

Guidance literature:

With potassium carbonate; In acetonitrile; for 24h; Heating;

DOI:10.1039/b702958f

Reference yield:

2-(benzyloxy)biphenyl-3-carbaldehyde (882533-05-3) → [1-(2-benzyloxy-biphenyl-3-yl)-ethyl]-bis-(2-benzyloxy-biphenyl-3-ylmethyl)-amine (938435-17-7)

Guidance literature:

Multi-step reaction with 3 steps

1: NaBH₄ / ethanol / 2.5 h / 20 °C

2: 85 percent / PBr₃ / toluene / 0 - 20 °C

3: 90 percent / K₂CO₃ / acetonitrile / 24 h / Heating

With sodium tetrahydroborate; phosphorus tribromide; potassium carbonate; In ethanol; toluene; acetonitrile;

DOI:10.1039/b702958f

Reference yield:

1-(2-benzyloxybiphenyl-3-yl)-methanol (938435-15-5) → [1-(2-benzyloxy-biphenyl-3-yl)-ethyl]-bis-(2-benzyloxy-biphenyl-3-ylmethyl)-amine (938435-17-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / PBr₃ / toluene / 0 - 20 °C

2: 90 percent / K₂CO₃ / acetonitrile / 24 h / Heating

With phosphorus tribromide; potassium carbonate; In toluene; acetonitrile;

DOI:10.1039/b702958f

upstream raw materials:

1-(2-benzyloxybiphenyl-3-yl)-methylbromide

2-(benzyloxy)biphenyl-3-carbaldehyde

1-(2-benzyloxybiphenyl-3-yl)-methanol

2-hydroxy-3-phenylbenzaldehyde

Downstream raw materials:

N(CH₂C₆H₃(C₆H₅)OH)2(CHCH₃C₆H₃(C₆H₅)OH)