Aprphine, 1,2-dimethoxy-, (+-)-

Base Information

Chemical Name:Aprphine, 1,2-dimethoxy-, (+-)-
CAS No.:5868-18-8
Molecular Formula:C₁₉H₂₁NO₂
Molecular Weight:295.381
Hs Code.:
DSSTox Substance ID:DTXSID80207378
Wikidata:Q83081273
ChEMBL ID:CHEMBL4289859

Synonyms:dl-Nuciferine;Aprphine, 1,2-dimethoxy-, (+-)-;(+-)-1,2-Dimethoxyaporphine;5868-18-8;4H-Dibenzo(de,g)quinoline, 5,6,6a,7-tetrahydro-1,2-dimethoxy-6-methyl-, (+-)-;1-5, 6-Dimethoxyaporphine;6a-.beta.-Aporphine, 1,2-dimethoxy-;CHEMBL4289859;DTXSID80207378;ORJVQPIHKOARKV-HNNXBMFYSA-N;LS-21470;FT-0686669;4H-Dibenzo(de,g)quinoline, 5,6,6a,7-tetrahydro-1,2-dimethoxy-6-methyl-

Suppliers and Price of Aprphine, 1,2-dimethoxy-, (+-)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Aprphine, 1,2-dimethoxy-, (+-)-

Chemical Property:

Vapor Pressure:1.27E-07mmHg at 25°C
Boiling Point:430.7°Cat760mmHg
Flash Point:151.9°C
Density:1.15g/cm³
XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:295.157228913
Heavy Atom Count:22
Complexity:401

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCC2=CC(=C(C3=C2C1CC4=CC=CC=C43)OC)OC
Isomeric SMILES:CN1CCC2=CC(=C(C3=C2[C@@H]1CC4=CC=CC=C43)OC)OC

Technology Process of Aprphine, 1,2-dimethoxy-, (+-)-

There total 11 articles about Aprphine, 1,2-dimethoxy-, (+-)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: (R)-1,2-dimethoxy-4,5,6a,7-tetrahydrodibenzo[de,g]quinoline-6-carboxylic acid methyl ester

: 475-83-2,5868-18-8,16654-38-9,37659-75-9
R-(-)-nuciferine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 24h;
DOI:10.1002/ejoc.200600674

Reference yield: 84.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 4846-19-9,20454-22-2,37659-74-8,54750-04-8
(6aR)-1,2-dimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline

: 475-83-2,5868-18-8,16654-38-9,37659-75-9
R-(-)-nuciferine

Guidance literature:: formaldehyd; (6aR)-1,2-dimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline; In methanol; water; at 20 ℃; for 0.5h;

With sodium tetrahydroborate; In methanol; water; at 20 ℃;
DOI:10.1016/j.tet.2020.131461