C₁₆H₁₆BrFN₂O₂

Base Information

Chemical Name:C₁₆H₁₆BrFN₂O₂
CAS No.:1355249-86-3
Molecular Formula:C₁₆H₁₆BrFN₂O₂
Molecular Weight:367.218
Hs Code.:

C<sub>16</sub>H<sub>16</sub>BrFN<sub>2</sub>O<sub>2</sub>

Synonyms:C₁₆H₁₆BrFN₂O₂

Suppliers and Price of C₁₆H₁₆BrFN₂O₂

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of C₁₆H₁₆BrFN₂O₂

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of C₁₆H₁₆BrFN₂O₂

There total 10 articles about C₁₆H₁₆BrFN₂O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1355249-85-2
C₁₆H₁₇FN₂O₂

: 1355249-86-3
C₁₆H₁₆BrFN₂O₂

Guidance literature:: With phenyltrimethylammonium tribromide; In chloroform; for 0.5h; Reflux;

Reference yield:

: 1355249-62-5
C₁₆H₁₈N₂O₃

: 1355249-86-3
C₁₆H₁₆BrFN₂O₂

Guidance literature:: Multi-step reaction with 9 steps

1.1: sodium hydroxide / methanol / 2 h / Reflux

1.2: pH 2 - 3

2.1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere

3.1: triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere

4.1: magnesium / tetrahydrofuran / 60 - 70 °C / Inert atmosphere

4.2: -78 - 20 °C / Inert atmosphere

5.1: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 18 h / Inert atmosphere; Reflux

6.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 5 h / 0 - 20 °C

7.1: hydrogen / palladium on activated charcoal / methanol / 12 h / 20 °C

8.1: diethylamino-sulfur trifluoride / dichloromethane / 0.5 h / -78 °C / Inert atmosphere

8.2: pH 8 - 9

9.1: phenyltrimethylammonium tribromide / chloroform / 0.5 h / Reflux

With oxalyl dichloride; diethylamino-sulfur trifluoride; hydrogen; phenyltrimethylammonium tribromide; magnesium; triethylamine; 3-chloro-benzenecarboperoxoic acid; sodium hydroxide; tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; palladium on activated charcoal; N,N-dimethyl-formamide; In tetrahydrofuran; methanol; dichloromethane; chloroform;

Reference yield:

: 1355249-61-4
ethyl 3-bromo-1-(4-methoxybenzyl)-1H-pyrazole-4-carboxylate

: 1355249-86-3
C₁₆H₁₆BrFN₂O₂

Guidance literature:: Multi-step reaction with 10 steps

1.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene / 6 h / Reflux

2.1: sodium hydroxide / methanol / 2 h / Reflux

2.2: pH 2 - 3

3.1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere

4.1: triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere

5.1: magnesium / tetrahydrofuran / 60 - 70 °C / Inert atmosphere

5.2: -78 - 20 °C / Inert atmosphere

6.1: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 18 h / Inert atmosphere; Reflux

7.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 5 h / 0 - 20 °C

8.1: hydrogen / palladium on activated charcoal / methanol / 12 h / 20 °C

9.1: diethylamino-sulfur trifluoride / dichloromethane / 0.5 h / -78 °C / Inert atmosphere

9.2: pH 8 - 9

10.1: phenyltrimethylammonium tribromide / chloroform / 0.5 h / Reflux

With oxalyl dichloride; diethylamino-sulfur trifluoride; hydrogen; phenyltrimethylammonium tribromide; magnesium; triethylamine; 3-chloro-benzenecarboperoxoic acid; sodium hydroxide; tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; palladium on activated charcoal; N,N-dimethyl-formamide; In tetrahydrofuran; methanol; dichloromethane; chloroform; toluene;