methyl α-phenyl-1-[4-[[[4'-(trifluoromethyl)[1,1'-biphenyl]-2-yl]carbonyl]amino]phenyl]-4-piperidineacetate trifluoroacetate

Base Information

Chemical Name:methyl α-phenyl-1-[4-[[[4'-(trifluoromethyl)[1,1'-biphenyl]-2-yl]carbonyl]amino]phenyl]-4-piperidineacetate trifluoroacetate
CAS No.:403987-30-4
Molecular Formula:C₂HF₃O₂*C₃₄H₃₁F₃N₂O₃
Molecular Weight:686.651
Hs Code.:

Synonyms:methyl α-phenyl-1-[4-[[[4'-(trifluoromethyl)[1,1'-biphenyl]-2-yl]carbonyl]amino]phenyl]-4-piperidineacetate trifluoroacetate

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Chemical Property of methyl α-phenyl-1-[4-[[[4'-(trifluoromethyl)[1,1'-biphenyl]-2-yl]carbonyl]amino]phenyl]-4-piperidineacetate trifluoroacetate

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Technology Process of methyl α-phenyl-1-[4-[[[4'-(trifluoromethyl)[1,1'-biphenyl]-2-yl]carbonyl]amino]phenyl]-4-piperidineacetate trifluoroacetate

There total 1 articles about methyl α-phenyl-1-[4-[[[4'-(trifluoromethyl)[1,1'-biphenyl]-2-yl]carbonyl]amino]phenyl]-4-piperidineacetate trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₉H₃₃N₂O₄Pol

: 84392-17-6
4'-(trifluoromethyl)-2-biphenylcarboxylic acid

: 76-05-1
trifluoroacetic acid

: 403987-30-4
methyl α-phenyl-1-[4-[[[4'-(trifluoromethyl)[1,1'-biphenyl]-2-yl]carbonyl]amino]phenyl]-4-piperidineacetate trifluoroacetate

Guidance literature:: 4'-(trifluoromethyl)-2-biphenylcarboxylic acid; With thionyl chloride; In dichloromethane; for 0.5h; Heating / reflux;

C₂₉H₃₃N₂O₄Pol; With dmap; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 21h;

trifluoroacetic acid; With chlorotriisopropylsilane; In dichloromethane; for 1h;