2-Hydroxypromazine

Base Information

Chemical Name:2-Hydroxypromazine
CAS No.:3926-64-5
Molecular Formula:C17H20N2OS
Molecular Weight:300.425
Hs Code.:2934300000
DSSTox Substance ID:DTXSID70192507
Nikkaji Number:J117.368E
Wikidata:Q83065190
Mol file:3926-64-5.mol

Synonyms:2-hydroxypromazine;2-OH-PZ

Suppliers and Price of 2-Hydroxypromazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
2-Hydroxy promazine
100mg
$ 4283.00

TRC
2-HydroxyPromazine
100mg
$ 1355.00

American Custom Chemicals Corporation
2-HYDROXY PROMAZINE 95.00%
10G
$ 2194.50

American Custom Chemicals Corporation
2-HYDROXY PROMAZINE 95.00%
1G
$ 721.88

Total 5 raw suppliers

Chemical Property of 2-Hydroxypromazine

Chemical Property:

Vapor Pressure:8.14E-10mmHg at 25°C
Melting Point:>58°C (dec.)
Boiling Point:479.4°Cat760mmHg
Flash Point:243.8°C
PSA：52.01000
Density:1.204g/cm³
LogP:4.01160
Storage Temp.:-20°C Freezer
Solubility.:Chloroform (Slightly, Heated), Methanol (Slightly, Sonicated)
XLogP3:4.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:300.12963444
Heavy Atom Count:21
Complexity:339

Purity/Quality:

98%Min ^*data from raw suppliers

2-Hydroxy promazine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)O
Uses A metabolite of Promazine (P756300).

Technology Process of 2-Hydroxypromazine

There total 4 articles about 2-Hydroxypromazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 50-53-3
2-chloro-N,N-dimethyl-10H-phenothiazine-10-propanamine

: 3926-64-5
10-[3-(dimethylamino)propyl]-10H-phenothiazin-2-ol

Guidance literature:: With dicyclohexyl[3,6-dimethoxy-2′,4′,6′-tris(1-methylethyl)[1,1′-biphenyl]-2-yl]phosphine; boric acid; palladium diacetate; caesium carbonate; In 1-methyl-pyrrolidin-2-one; at 100 ℃; for 14h; Schlenk technique; Inert atmosphere;
DOI:10.1021/acs.orglett.0c03069

Reference yield: 38.0%

: 69-09-0
chlorpromazine hydrochloride

: 3926-64-5
10-[3-(dimethylamino)propyl]-10H-phenothiazin-2-ol

: 58-40-2
promazine

Guidance literature:: In water; Irradiation;
DOI:10.1039/P29830001313

Reference yield:

: 3926-64-5
10-[3-(dimethylamino)propyl]-10H-phenothiazin-2-ol

: 3926-64-5
C₁₇H₂₀N₂OS⁽¹⁺⁾

Guidance literature:: With perchloric acid; Manganase-(III) solution; In water; at 7 ℃; Kinetics; Mechanism; Rate constant; activation parameters;
DOI:10.1039/DT9800000484