(S)-5-bromo-4-fluoro-N-(1-(4-fluorophenyl)ethyl)-2-nitrobenzenamine

Base Information

• Chemical Name: (S)-5-bromo-4-fluoro-N-(1-(4-fluorophenyl)ethyl)-2-nitrobenzenamine
• CAS No.: 907218-72-8
• Molecular Formula: C₁₄H₁₁BrF₂N₂O₂
• Molecular Weight: 357.154
• Mol file: 907218-72-8.mol

Synonyms:(S)-5-bromo-4-fluoro-N-(1-(4-fluorophenyl)ethyl)-2-nitrobenzenamine

Chemical Property of (S)-5-bromo-4-fluoro-N-(1-(4-fluorophenyl)ethyl)-2-nitrobenzenamine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of (S)-5-bromo-4-fluoro-N-(1-(4-fluorophenyl)ethyl)-2-nitrobenzenamine

There total 1 articles about (S)-5-bromo-4-fluoro-N-(1-(4-fluorophenyl)ethyl)-2-nitrobenzenamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

(S)-1-(4-Fluoro-phenyl)-ethylamine (66399-30-2) + 1-bromo-2,5-difluoro-4-nitrobenzene (167415-27-2) → (S)-5-bromo-4-fluoro-N-(1-(4-fluorophenyl)ethyl)-2-nitrobenzenamine (907218-72-8)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In butan-1-ol; at 80 ℃; for 17h;

Reference yield:

(S)-5-bromo-4-fluoro-N-(1-(4-fluorophenyl)ethyl)-2-nitrobenzenamine (907218-72-8) → (S)-5-bromo-4-fluoro-N1-(1-(4-fluorophenyl)ethyl)benzene-1,2-diamine (907218-71-7)

Guidance literature:

(S)-5-bromo-4-fluoro-N-(1-(4-fluorophenyl)ethyl)-2-nitrobenzenamine; With ammonium chloride; zinc; In tetrahydrofuran; methanol; water; at 25 ℃; for 2h;

With ammonium acetate; In tetrahydrofuran; methanol; water; for 0.5h;

upstream raw materials:

(S)-1-(4-Fluoro-phenyl)-ethylamine

1-bromo-2,5-difluoro-4-nitrobenzene

Downstream raw materials:

(S)-5-bromo-4-fluoro-N₁-(1-(4-fluorophenyl)ethyl)benzene-1,2-diamine