(2S,3R,4R)-3,4-bis(benzyloxy)-2-((benzyloxy)methyl)piperidine

Base Information

• Chemical Name: (2S,3R,4R)-3,4-bis(benzyloxy)-2-((benzyloxy)methyl)piperidine
• CAS No.: 366815-78-3
• Molecular Formula: C₂₇H₃₁NO₃
• Molecular Weight: 417.548
• Mol file: 366815-78-3.mol

Synonyms:(2S,3R,4R)-3,4-bis(benzyloxy)-2-((benzyloxy)methyl)piperidine

Chemical Property of (2S,3R,4R)-3,4-bis(benzyloxy)-2-((benzyloxy)methyl)piperidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2S,3R,4R)-3,4-bis(benzyloxy)-2-((benzyloxy)methyl)piperidine

There total 11 articles about (2S,3R,4R)-3,4-bis(benzyloxy)-2-((benzyloxy)methyl)piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

(2S,3R,4R)-3,4-bis(benzyloxy)-2-(benzyloxymethyl)-1-(4-nitrophenylsulfonyl)piperidine (1129725-85-4) → (2S,3R,4R)-3,4-bis(benzyloxy)-2-((benzyloxy)methyl)piperidine (366815-78-3)

Guidance literature:

With potassium carbonate; thiophenol; In acetonitrile; at 20 ℃; for 5h;

DOI:10.1002/ejoc.200800796

Reference yield:

C28H35NO6S*ClH → (2S,3R,4R)-3,4-bis(benzyloxy)-2-((benzyloxy)methyl)piperidine (366815-78-3)

Guidance literature:

With potassium carbonate; In acetonitrile; for 4h; Reflux;

DOI:10.1016/j.tetlet.2016.02.046

Reference yield:

3,4-bis-benzyloxy-2-benzyloxymethyl-3,4-dihydro-2H-pyridine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester → (2S,3R,4R)-3,4-bis(benzyloxy)-2-((benzyloxy)methyl)piperidine (366815-78-3)

Guidance literature:

With morpholine; hydrogen; palladium on activated charcoal; In ethanol;

DOI:10.1055/s-2001-16039

upstream raw materials:

((1S,2R,3R)-2,3-Bis-benzyloxy-1-benzyloxymethyl-hex-5-enyl)-carbamic acid 9H-fluoren-9-ylmethyl ester

(2S,3R,4R)-3,4-bis(benzyloxy)-2-(benzyloxymethyl)-1-(4-nitrophenylsulfonyl)piperidine

3,4,6-tri-O-benzyl-2-deoxy-D-glucopyranose

3,4,6-tri-O-benzyl-D-glucal

Downstream raw materials:

(2S,3R,4R)-2-(hydroxymethyl)piperidine-3,4-diol