morpholinium salt of α-morpholino-β-hexahydrobenzoylpropionic acid

Base Information

• Chemical Name: morpholinium salt of α-morpholino-β-hexahydrobenzoylpropionic acid
• CAS No.: 112895-81-5
• Molecular Formula: C₄H₉NO*C₁₄H₂₃NO₄
• Molecular Weight: 356.462
• Mol file: 112895-81-5.mol

Synonyms:morpholinium salt of α-morpholino-β-hexahydrobenzoylpropionic acid

Chemical Property of morpholinium salt of α-morpholino-β-hexahydrobenzoylpropionic acid

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of morpholinium salt of α-morpholino-β-hexahydrobenzoylpropionic acid

There total 1 articles about morpholinium salt of α-morpholino-β-hexahydrobenzoylpropionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

morpholine (110-91-8,99108-56-2) + Cyclohexyl methyl ketone (823-76-7) + Glyoxilic acid (298-12-4) → morpholinium salt of α-morpholino-β-hexahydrobenzoylpropionic acid (112895-81-5)

Guidance literature:

In ethanol; a) RT, 1h, b) 60 deg C, 6 h7;

DOI:10.1021/jm00385a003

Reference yield: 78.0%

morpholinium salt of α-morpholino-β-hexahydrobenzoylpropionic acid (112895-81-5) → 6-cyclohexyl-3(2H)-pyridazinone (105537-90-4)

Guidance literature:

With hydrazine hydrate; In butan-1-ol; a) RT, 1h, b) reflux, overnight;

DOI:10.1021/jm00385a003

Reference yield: 50.0%

morpholinium salt of α-morpholino-β-hexahydrobenzoylpropionic acid (112895-81-5) → trans-β-hexahydrobenzoylacrylic acid (112895-82-6)

Guidance literature:

With acetic anhydride; acetic acid; for 10h; Heating;

DOI:10.1021/jm00400a001

upstream raw materials:

morpholine

Cyclohexyl methyl ketone

Glyoxilic acid

Downstream raw materials:

6-cyclohexyl-3(2H)-pyridazinone

trans-β-hexahydrobenzoylacrylic acid

(E)-4-Cyclohexyl-4-hydroxy-but-2-enoic acid

6-Cyclohexyl-pyridazin-3-ylamine