12-Tetracosanone,13-hydroxy-

Base Information

• Chemical Name: 12-Tetracosanone,13-hydroxy-
• CAS No.: 6537-38-8
• Molecular Formula: C₂₄H₄₈O₂
• Molecular Weight: 368.644
• Mol file: 6537-38-8.mol

Synonyms:Lauroin

Chemical Property of 12-Tetracosanone,13-hydroxy-

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 12-Tetracosanone,13-hydroxy-

There total 1 articles about 12-Tetracosanone,13-hydroxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

S-(2-pyridyl) dodecanethioate (75560-84-8) → 13-hydroxytetracosan-12-one (6537-38-8) + tetracosane-12,13-dione (61136-78-5)

Guidance literature:

With hydrogenchloride; bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; In N,N-dimethyl-formamide; toluene; at 40 ℃; for 1h;

DOI:10.1246/cl.1980.905

Reference yield: 91.0%

13-hydroxytetracosan-12-one (6537-38-8) → tetracosane-12,13-dione (61136-78-5)

Guidance literature:

With oxygen; vanadium(V) oxychloride; In acetonitrile; at 20 - 65 ℃; for 21h;

DOI:10.1039/c4cc00654b

Reference yield:

13-hydroxytetracosan-12-one (6537-38-8) → 1,3-di(2,6-diisopropylphenyl)-4,5-diundecylimidazolium bromide

Guidance literature:

Multi-step reaction with 3 steps

1.1: tetrabutylammomium bromide; 2,3-dicyano-5,6-dichloro-p-benzoquinone; triphenylphosphine / dichloromethane / 16 h / 20 °C / Inert atmosphere

2.1: N-ethyl-N,N-diisopropylamine / acetonitrile / 72 h / 120 °C / Inert atmosphere

2.2: 20 h / 90 °C / Inert atmosphere

3.1: potassium carbonate / acetone / 6 h / 60 °C / Inert atmosphere

With tetrabutylammomium bromide; potassium carbonate; N-ethyl-N,N-diisopropylamine; triphenylphosphine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In dichloromethane; acetone; acetonitrile;

DOI:10.1002/chem.201502542

upstream raw materials:

S-(2-pyridyl) dodecanethioate

Downstream raw materials:

tetracosane-12,13-dione

1,3-dibenzyl-4,5-diundecylimidazol-3-ium bromide

1,3-bis(2,6-diisopropylphenyl)-4,5-diundecyl-imidazolium bromide