(E)-N-(2-hydroxybenzylidene)-1,4-dioxo-3,4-dihydrophthalazine-2(1H)-carbothioamide

Base Information

• Chemical Name: (E)-N-(2-hydroxybenzylidene)-1,4-dioxo-3,4-dihydrophthalazine-2(1H)-carbothioamide
• CAS No.: 1372122-48-9
• Molecular Formula: C₁₆H₁₁N₃O₃S
• Molecular Weight: 325.348
• Mol file: 1372122-48-9.mol

Synonyms:(E)-N-(2-hydroxybenzylidene)-1,4-dioxo-3,4-dihydrophthalazine-2(1H)-carbothioamide

Chemical Property of (E)-N-(2-hydroxybenzylidene)-1,4-dioxo-3,4-dihydrophthalazine-2(1H)-carbothioamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-N-(2-hydroxybenzylidene)-1,4-dioxo-3,4-dihydrophthalazine-2(1H)-carbothioamide

There total 1 articles about (E)-N-(2-hydroxybenzylidene)-1,4-dioxo-3,4-dihydrophthalazine-2(1H)-carbothioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

salicylaldehyde (90-02-8) + 1,4-dioxo-3,4-dihydrophthalazine-2(1H)-carbothioamide → (E)-N-(2-hydroxybenzylidene)-1,4-dioxo-3,4-dihydrophthalazine-2(1H)-carbothioamide (1372122-48-9)

Guidance literature:

In ethanol; Reflux;

DOI:10.1016/j.saa.2012.02.041

Reference yield:

manganese(II) chloride tetrahydrate + (E)-N-(2-hydroxybenzylidene)-1,4-dioxo-3,4-dihydrophthalazine-2(1H)-carbothioamide (1372122-48-9) → [MnCl2(H2O)((E)-N-(2-hydroxybenzylidene)-1,4-dioxo-3,4-dihydrophthalazine-2(1H)-carbothioamide)]

Guidance literature:

In ethanol; mixt. of ligand and Mn salt in EtOH was heated at 70-80°C for 3-4h; aq. ammonia adde to pH 6; filtered; washed (EtOH); dried (CaCl2); elem. anal.;

DOI:10.1016/j.saa.2012.02.041

upstream raw materials:

salicylaldehyde