2-fluoro-4-{5-[1-(3-isopropyl-[1,2,4]oxadiazol-5-ylmethyl)azetidin-3-yloxy]-pyridin-2-yl}benzoate sodium salt

Base Information

Chemical Name:2-fluoro-4-{5-[1-(3-isopropyl-[1,2,4]oxadiazol-5-ylmethyl)azetidin-3-yloxy]-pyridin-2-yl}benzoate sodium salt
CAS No.:1146089-88-4
Molecular Formula:C₂₁H₂₀FN₄O₄*Na
Molecular Weight:434.402
Hs Code.:

Synonyms:2-fluoro-4-{5-[1-(3-isopropyl-[1,2,4]oxadiazol-5-ylmethyl)azetidin-3-yloxy]-pyridin-2-yl}benzoate sodium salt

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Chemical Property of 2-fluoro-4-{5-[1-(3-isopropyl-[1,2,4]oxadiazol-5-ylmethyl)azetidin-3-yloxy]-pyridin-2-yl}benzoate sodium salt

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Technology Process of 2-fluoro-4-{5-[1-(3-isopropyl-[1,2,4]oxadiazol-5-ylmethyl)azetidin-3-yloxy]-pyridin-2-yl}benzoate sodium salt

There total 1 articles about 2-fluoro-4-{5-[1-(3-isopropyl-[1,2,4]oxadiazol-5-ylmethyl)azetidin-3-yloxy]-pyridin-2-yl}benzoate sodium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1146089-87-3
2-fluoro-4-{5-[1-(3-isopropyl-[1,2,4]oxadiazol-5-ylmethyl)azetidin-3-yloxy]-pyridin-2-yl}benzoic acid ethyl ester

: 1146089-88-4
2-fluoro-4-{5-[1-(3-isopropyl-[1,2,4]oxadiazol-5-ylmethyl)azetidin-3-yloxy]-pyridin-2-yl}benzoate sodium salt

Guidance literature:: With sodium hydroxide; water; In ethanol; at 20 ℃; for 16h;

Reference yield:

: 1146089-88-4
2-fluoro-4-{5-[1-(3-isopropyl-[1,2,4]oxadiazol-5-ylmethyl)azetidin-3-yloxy]-pyridin-2-yl}benzoate sodium salt

: 1146089-23-7
2-fluoro-4-{5-[1-(3-isopropyl-[1,2,4]oxadiazol-5-ylmethyl)azetidin-3-yloxy]pyridin-2-yl}benzamide

Guidance literature:: With ammonia; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide; at 20 - 40 ℃; for 32h;