5-Chloro-2-methyl-1-phenyl-1H-benzimidazole

Base Information

Chemical Name:5-Chloro-2-methyl-1-phenyl-1H-benzimidazole
CAS No.:84100-59-4
Molecular Formula:C14H11ClN2
Molecular Weight:242.708
Hs Code.:2933990090
European Community (EC) Number:282-139-9
NSC Number:97074
DSSTox Substance ID:DTXSID60232986
Nikkaji Number:J297.523H
Wikidata:Q83114248
ChEMBL ID:CHEMBL1407958
Mol file:84100-59-4.mol

Synonyms:5-Chloro-2-methyl-1-phenyl-1H-benzimidazole;84100-59-4;EINECS 282-139-9;Benzimidazole, 5-chloro-2-methyl-1-phenyl-;5-Chloro-2-methyl-1-phenyl-1H-benzoimidazole;NSC97074;TimTec1_007113;MLS000523736;SCHEMBL541394;CHEMBL1407958;DTXSID60232986;HMS1554D07;HMS2378G20;NSC 97074;NSC-97074;STK327688;AKOS000546996;NCGC00244982-01;SMR000122809

Suppliers and Price of 5-Chloro-2-methyl-1-phenyl-1H-benzimidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of 5-Chloro-2-methyl-1-phenyl-1H-benzimidazole

Chemical Property:

Vapor Pressure:5.61E-07mmHg at 25°C
Boiling Point:411.4°Cat760mmHg
Flash Point:202.6°C
PSA：17.82000
Density:1.23g/cm³
LogP:3.98730
XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:242.0610761
Heavy Atom Count:17
Complexity:265

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC2=C(N1C3=CC=CC=C3)C=CC(=C2)Cl

Technology Process of 5-Chloro-2-methyl-1-phenyl-1H-benzimidazole

There total 5 articles about 5-Chloro-2-methyl-1-phenyl-1H-benzimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 103-84-4
Acetanilid

: 89-61-2
2,5-dichloronitrobenzene

: 84100-59-4
5-chloro-2-methyl-1-phenyl-1H-benzoimidazole

Guidance literature:: Acetanilid; 2,5-dichloronitrobenzene; With palladium(II) trifluoroacetate; caesium carbonate; (R)-2,2'-bis(diphenylphosphanyl)-1,1'-binaphthyl; In toluene; at 80 ℃; for 18h; Inert atmosphere;

With iron; acetic acid; In toluene; for 0.5h; Reflux;
DOI:10.1002/ejoc.201001423

Reference yield: 77.0%

: 861342-91-8
N-(5-chloro-2-nitro-phenyl)-N-phenyl-acetamide

: 84100-59-4
5-chloro-2-methyl-1-phenyl-1H-benzoimidazole

Guidance literature:: N-(5-chloro-2-nitro-phenyl)-N-phenyl-acetamide; With iron; acetic acid; for 0.5h; Heating / reflux;

With sodium hydrogencarbonate; In water; Product distribution / selectivity;

Reference yield: 56.0%

: 41513-04-6
2-chloro-5-bromonitrobenzene

: 103-84-4
Acetanilid

: 84100-59-4
5-chloro-2-methyl-1-phenyl-1H-benzoimidazole

Guidance literature:: 2-chloro-5-bromonitrobenzene; Acetanilid; With potassium phosphate; N-methyl-ethane-1,2-diamine; copper(l) iodide; In toluene; at 100 ℃; for 18h;

With water; In toluene;

With iron; sodium hydrogencarbonate; acetic acid; more than 3 stages; Product distribution / selectivity;