N-[2-[(4-chlorophenyl)methyleneamino]phenyl]-2-pyrrolidin-1-yl-acetamide

Base Information

• Chemical Name: N-[2-[(4-chlorophenyl)methyleneamino]phenyl]-2-pyrrolidin-1-yl-acetamide
• CAS No.: 109037-60-7
• Molecular Formula: C₁₉H₂₀ClN₃O
• Molecular Weight: 341.84
• Mol file: 109037-60-7.mol

Synonyms:pyrrolidino-acetic acid-[2-(4-chloro-benzylidenamino)-anilide]

Chemical Property of N-[2-[(4-chlorophenyl)methyleneamino]phenyl]-2-pyrrolidin-1-yl-acetamide

Chemical Property:

• Vapor Pressure: 1.6E-12mmHg at 25°C
• Water Solubility.: 8.19mg/L at 25℃

Purity/Quality:

99.9% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-[2-[(4-chlorophenyl)methyleneamino]phenyl]-2-pyrrolidin-1-yl-acetamide

There total 3 articles about N-[2-[(4-chlorophenyl)methyleneamino]phenyl]-2-pyrrolidin-1-yl-acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-chloro-N-(2-nitrophenyl)acetamide (10147-70-3) → pyrrolidino-acetic acid-[2-(4-chloro-benzylidenamino)-anilide] (109037-60-7)

Guidance literature:

Multi-step reaction with 3 steps

1: toluene

2: methanol; nickel / 40 °C / Hydrogenation

3: piperidine; methanol

With piperidine; methanol; nickel; toluene;

Reference yield:

pyrrolidino-acetic acid-(2-nitro-anilide) (100138-78-1) → pyrrolidino-acetic acid-[2-(4-chloro-benzylidenamino)-anilide] (109037-60-7)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol; nickel / 40 °C / Hydrogenation

2: piperidine; methanol

With piperidine; methanol; nickel;

Reference yield:

pyrrolidino-acetic acid-(2-amino-anilide) (91646-50-3) + 4-chlorobenzaldehyde (104-88-1) → pyrrolidino-acetic acid-[2-(4-chloro-benzylidenamino)-anilide] (109037-60-7)

Guidance literature:

With piperidine; methanol;

upstream raw materials:

pyrrolidino-acetic acid-(2-amino-anilide)

4-chlorobenzaldehyde

2-chloro-N-(2-nitrophenyl)acetamide

pyrrolidino-acetic acid-(2-nitro-anilide)

Downstream raw materials:

clemizole

pyrrolidino-acetic acid-[2-(4-chloro-benzylamino)-anilide]