Avermectin B2a

Base Information

Chemical Name:Avermectin B2a
CAS No.:135680-93-2
Molecular Formula:C48H74O15
Molecular Weight:891.0922
Hs Code.:
European Community (EC) Number:810-513-9
UNII:FUJ4Z758WB
DSSTox Substance ID:DTXSID90860913
Wikidata:Q104971234
Mol file:135680-93-2.mol

Synonyms:avermectin B2a

Suppliers and Price of Avermectin B2a

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(13R,23S)-22,23-DIHYDRO-5-O-DEMETHYL-23-HYDROXYAVERMECTIN A1A 95.00%
5MG
$ 497.99

Total 1 raw suppliers

Chemical Property of Avermectin B2a

Chemical Property:

Boiling Point:966.4°Cat760mmHg
Flash Point:275.1°C
PSA：190.29000
Density:1.26g/cm³
LogP:4.57220
XLogP3:3.2
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:15
Rotatable Bond Count:8
Exact Mass:890.50277165
Heavy Atom Count:63
Complexity:1720

Purity/Quality:

98% ^*data from raw suppliers

(13R,23S)-22,23-DIHYDRO-5-O-DEMETHYL-23-HYDROXYAVERMECTIN A1A 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(C)C1C(C(CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)O)C
Isomeric SMILES:CC[C@H](C)[C@@H]1[C@H]([C@H](C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)O)C

Technology Process of Avermectin B2a

There total 2 articles about Avermectin B2a which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 78017-92-2,135757-90-3
5-ketoavermectin B_2a

: 65195-57-5,135680-93-2,144176-51-2
avermectin B_2a

Guidance literature:: With sodium tetrahydroborate; In ethanol; at -15 ℃; for 0.333333h; Yield given;
DOI:10.1021/jo00365a039

Reference yield:

: 65195-53-1
avermectin A_2a

: 65195-57-5,135680-93-2,144176-51-2
avermectin B_2a

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) toluene, 100 deg C, 40 min, 2.) AcOH, 18 deg C, 5 h

2: NaBH₄ / ethanol / 0.33 h / -15 °C

With sodium tetrahydroborate; In ethanol;
DOI:10.1021/jo00365a039