C₅₃H₉₂N₆O₁₇

Base Information

• Chemical Name: C₅₃H₉₂N₆O₁₇
• CAS No.: 1259518-81-4
• Molecular Formula: C₅₃H₉₂N₆O₁₇
• Molecular Weight: 1085.34
• Mol file: 1259518-81-4.mol

Synonyms:C₅₃H₉₂N₆O₁₇

Chemical Property of C₅₃H₉₂N₆O₁₇

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₃H₉₂N₆O₁₇

There total 7 articles about C₅₃H₉₂N₆O₁₇ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

methyl galloate (99-24-1) + N,N'-di-t-butoxycarbonyl-2-(2-bromoethyl)-1,3-diaminopropane (167502-34-3) → C53H92N6O17 (1259518-81-4)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 24h;

DOI:10.1021/jal086112

Reference yield:

C14H22O7S2 (1292296-26-4) → C53H92N6O17 (1259518-81-4)

Guidance literature:

Multi-step reaction with 5 steps

1.1: sodium azide / N,N-dimethyl-formamide / 18 h / 50 °C

1.2: 20 - 50 °C

2.1: sodium hydroxide / water / 0 - 20 °C / pH 10

3.1: hydrogen; palladium(II) hydroxide / methanol / 4.5 h / 20 °C / Inert atmosphere

4.1: carbon tetrabromide; triphenylphosphine / tetrahydrofuran / 0 - 20 °C

5.1: potassium carbonate / N,N-dimethyl-formamide / 24 h / 80 °C

With sodium azide; carbon tetrabromide; hydrogen; palladium(II) hydroxide; potassium carbonate; triphenylphosphine; sodium hydroxide; In tetrahydrofuran; methanol; water; N,N-dimethyl-formamide;

DOI:10.1021/jal086112

Reference yield:

Diethyl<(2-benzyloxy)ethyl>malonate (41478-45-9) → C53H92N6O17 (1259518-81-4)

Guidance literature:

Multi-step reaction with 7 steps

1.1: lithium aluminium tetrahydride / tetrahydrofuran / 12 h / Reflux

2.1: triethylamine / dichloromethane / 0 - 20 °C

3.1: sodium azide / N,N-dimethyl-formamide / 18 h / 50 °C

3.2: 20 - 50 °C

4.1: sodium hydroxide / water / 0 - 20 °C / pH 10

5.1: hydrogen; palladium(II) hydroxide / methanol / 4.5 h / 20 °C / Inert atmosphere

6.1: carbon tetrabromide; triphenylphosphine / tetrahydrofuran / 0 - 20 °C

7.1: potassium carbonate / N,N-dimethyl-formamide / 24 h / 80 °C

With lithium aluminium tetrahydride; sodium azide; carbon tetrabromide; hydrogen; palladium(II) hydroxide; potassium carbonate; triethylamine; triphenylphosphine; sodium hydroxide; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide;

DOI:10.1021/jal086112

upstream raw materials:

C₁₄H₂₂O₇S₂

Diethyl<(2-benzyloxy)ethyl>malonate

methyl galloate

N,N'-di-t-butoxycarbonyl-2-(2-bromoethyl)-1,3-diaminopropane

Downstream raw materials:

C₅₂H₉₀N₆O₁₇

C₅₉H₁₀₃N₇O₁₈

C₅₈H₁₀₁N₇O₁₈