Technology Process of 6-cyano-2,2-diphenyl-[2H]-pyran[5,6-c]dibenzothiophene
There total 4 articles about 6-cyano-2,2-diphenyl-[2H]-pyran[5,6-c]dibenzothiophene which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
1,1'-bis-(diphenylphosphino)ferrocene; tris(dibenzylideneacetone)dipalladium (0);
In
N,N-dimethyl-formamide;
at 90 ℃;
for 5h;
DOI:10.1016/S0040-4020(02)00023-6
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 59 percent / n-BuLi; B(OBu)3; 10 percent H2O2
2.1: NaH; CH3I / dimethylformamide
2.2: Br2 / acetic acid
2.3: 72 percent / BBr3 / CH2Cl2 / -80 °C
3.1: 86 percent / p-toluenesulfonic acid / CH2Cl2 / 3.5 h / Heating
4.1: 30 percent / 1,1'-bis(diphenylphosphin) ferrocene; Pd2(dba)3 / dimethylformamide / 5 h / 90 °C
With
1,1'-bis-(diphenylphosphino)ferrocene; n-butyllithium; tris(dibenzylideneacetone)dipalladium (0); boric acid tributyl ester; dihydrogen peroxide; sodium hydride; toluene-4-sulfonic acid; methyl iodide;
In
dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(02)00023-6
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: NaH; CH3I / dimethylformamide
1.2: Br2 / acetic acid
1.3: 72 percent / BBr3 / CH2Cl2 / -80 °C
2.1: 86 percent / p-toluenesulfonic acid / CH2Cl2 / 3.5 h / Heating
3.1: 30 percent / 1,1'-bis(diphenylphosphin) ferrocene; Pd2(dba)3 / dimethylformamide / 5 h / 90 °C
With
1,1'-bis-(diphenylphosphino)ferrocene; tris(dibenzylideneacetone)dipalladium (0); sodium hydride; toluene-4-sulfonic acid; methyl iodide;
In
dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(02)00023-6
