methyl O-(1,1-dimethylethyl)-N-{[4'-(methyloxy)-3-({[(2,4,6-trimethylphenyl)amino]carbonyl}amino)-4-biphenylyl]carbonyl}-L-threoninate

Base Information

Chemical Name:methyl O-(1,1-dimethylethyl)-N-{[4'-(methyloxy)-3-({[(2,4,6-trimethylphenyl)amino]carbonyl}amino)-4-biphenylyl]carbonyl}-L-threoninate
CAS No.:887244-00-0
Molecular Formula:C₃₃H₄₁N₃O₆
Molecular Weight:575.705
Hs Code.:

Synonyms:methyl O-(1,1-dimethylethyl)-N-{[4'-(methyloxy)-3-({[(2,4,6-trimethylphenyl)amino]carbonyl}amino)-4-biphenylyl]carbonyl}-L-threoninate

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Chemical Property of methyl O-(1,1-dimethylethyl)-N-{[4'-(methyloxy)-3-({[(2,4,6-trimethylphenyl)amino]carbonyl}amino)-4-biphenylyl]carbonyl}-L-threoninate

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Technology Process of methyl O-(1,1-dimethylethyl)-N-{[4'-(methyloxy)-3-({[(2,4,6-trimethylphenyl)amino]carbonyl}amino)-4-biphenylyl]carbonyl}-L-threoninate

There total 2 articles about methyl O-(1,1-dimethylethyl)-N-{[4'-(methyloxy)-3-({[(2,4,6-trimethylphenyl)amino]carbonyl}amino)-4-biphenylyl]carbonyl}-L-threoninate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 887243-99-4
methyl N-{[3-amino-4'-(methyloxy)-4-biphenylyl]carbonyl}-O-(1,1-dimethylethyl)-L-threoninate

: 2958-62-5
mesityl isocyanate

: 887244-00-0
methyl O-(1,1-dimethylethyl)-N-{[4'-(methyloxy)-3-({[(2,4,6-trimethylphenyl)amino]carbonyl}amino)-4-biphenylyl]carbonyl}-L-threoninate

Guidance literature:: With pyridine; at 20 ℃;

Reference yield:

: 887243-99-4
methyl N-{[3-amino-4'-(methyloxy)-4-biphenylyl]carbonyl}-O-(1,1-dimethylethyl)-L-threoninate

: 6784-26-5
2-isocyanato-1,3,5-trimethylbenzene

: 887244-00-0
methyl O-(1,1-dimethylethyl)-N-{[4'-(methyloxy)-3-({[(2,4,6-trimethylphenyl)amino]carbonyl}amino)-4-biphenylyl]carbonyl}-L-threoninate

Guidance literature:: With pyridine;
DOI:10.1016/j.bmcl.2008.12.085

Reference yield: 86.0%

: 887244-00-0
methyl O-(1,1-dimethylethyl)-N-{[4'-(methyloxy)-3-({[(2,4,6-trimethylphenyl)amino]carbonyl}amino)-4-biphenylyl]carbonyl}-L-threoninate

: 887239-23-8
O-(1,1-dimethylethyl)-N-{[4'-(methyloxy)-3-({[(2,4,6-trimethylphenyl)amino]carbonyl}amino)-4-biphenylyl]carbonyl}-L-threonine

Guidance literature:: methyl O-(1,1-dimethylethyl)-N-{[4'-(methyloxy)-3-({[(2,4,6-trimethylphenyl)amino]carbonyl}amino)-4-biphenylyl]carbonyl}-L-threoninate; With methanol; lithium hydroxide; water; In tetrahydrofuran; at 20 ℃;

With hydrogenchloride; In water;