3,5-bis-O-(tert-butyldiphenylsilyl)-C1-vinyl-2-deoxy-α-D-ribofuranose

Base Information

• Chemical Name: 3,5-bis-O-(tert-butyldiphenylsilyl)-C1-vinyl-2-deoxy-α-D-ribofuranose
• CAS No.: 1101167-39-8
• Molecular Formula: C₃₉H₄₈O₃Si₂
• Molecular Weight: 620.979
• Mol file: 1101167-39-8.mol

Synonyms:3,5-bis-O-(tert-butyldiphenylsilyl)-C1-vinyl-2-deoxy-α-D-ribofuranose

Chemical Property of 3,5-bis-O-(tert-butyldiphenylsilyl)-C1-vinyl-2-deoxy-α-D-ribofuranose

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 3,5-bis-O-(tert-butyldiphenylsilyl)-C1-vinyl-2-deoxy-α-D-ribofuranose

There total 1 articles about 3,5-bis-O-(tert-butyldiphenylsilyl)-C1-vinyl-2-deoxy-α-D-ribofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

(2R,3R,5R)-2,5-dihydroxy-1,3-bis-[tert-butyldiphenylsilyloxy]-hept-6-ene → 3,5-bis-O-(tert-butyldiphenylsilyl)-C1-vinyl-2-deoxy-α-D-ribofuranose (1101167-39-8)

Guidance literature:

With pyridine; methanesulfonyl chloride; In dichloromethane; at -20 ℃;

DOI:10.1021/jo801910u

Reference yield: 67.0%

4-vinyl-5-methyl-oxazol-2-one (1101167-43-4) + 3,5-bis-O-(tert-butyldiphenylsilyl)-C1-vinyl-2-deoxy-α-D-ribofuranose (1101167-39-8) → 4-[(E)-2-(3,5-bis-O-(tert-butyldiphenylsilyl)-2-deoxy-α-D-ribofuranosyl)vinyl]-5-methyl-oxazol-2-one (1101167-45-6)

Guidance literature:

With dichloro(o-isporopoxyphenylmethylene)(triphenylphosphine)ruthenium(II); In dichloromethane; for 8h; Inert atmosphere; Reflux;

DOI:10.1021/jo801910u

Downstream raw materials:

4-[(E)-2-(3,5-bis-O-(tert-butyldiphenylsilyl)-2-deoxy-α-D-ribofuranosyl)vinyl]-5-methyl-oxazol-2-one