S-(-)-dietilester dell'acido γ-butirrolatton-γ-metilenmalonico

Base Information

• Chemical Name: S-(-)-dietilester dell'acido γ-butirrolatton-γ-metilenmalonico
• CAS No.: 99393-07-4
• Molecular Formula: C₁₂H₁₈O₆
• Molecular Weight: 258.271
• Mol file: 99393-07-4.mol

Synonyms:S-(-)-dietilester dell'acido γ-butirrolatton-γ-metilenmalonico

Chemical Property of S-(-)-dietilester dell'acido γ-butirrolatton-γ-metilenmalonico

Chemical Property:

Purity/Quality:

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Technology Process of S-(-)-dietilester dell'acido γ-butirrolatton-γ-metilenmalonico

There total 1 articles about S-(-)-dietilester dell'acido γ-butirrolatton-γ-metilenmalonico which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(5S)-5-(hydroxymethyl)-2-oxo-tetrahydrofuran (32780-06-6) → S-(-)-dietilester dell'acido γ-butirrolatton-γ-metilenmalonico (99393-07-4)

Guidance literature:

Multi-step reaction with 2 steps

1: PBr₃ / CH₂Cl₂ / -20 °C

2: 3.5 g / sodium / ethanol / 2 h / Heating

With sodium; phosphorus tribromide; In ethanol; dichloromethane;

Reference yield:

S-(-)-dietilester dell'acido γ-butirrolatton-γ-metilenmalonico (99393-07-4) → 3-(5-oxotetrahydro-2-furanyl)propanoic acid (6283-72-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.8 g / H₂O, NaCl / dimethylsulfoxide / 6 h / 145 - 180 °C

2: methanesulfonic acid, formic acid / 6 h / Heating

With formic acid; methanesulfonic acid; water; sodium chloride; In dimethyl sulfoxide;

upstream raw materials:

(5S)-5-(hydroxymethyl)-2-oxo-tetrahydrofuran

Downstream raw materials:

3-(5-oxotetrahydro-2-furanyl)propanoic acid