Toluene-4-sulfonic acid (8R,9S,13R,14S,16S,17S)-3-methoxy-13-methyl-17-(tetrahydro-pyran-2-yloxy)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-16-ylmethyl ester

Base Information

Chemical Name:Toluene-4-sulfonic acid (8R,9S,13R,14S,16S,17S)-3-methoxy-13-methyl-17-(tetrahydro-pyran-2-yloxy)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-16-ylmethyl ester
CAS No.:618457-34-4
Molecular Formula:C₃₂H₄₂O₆S
Molecular Weight:554.748
Hs Code.:

Toluene-4-sulfonic acid (8R,9S,13R,14S,16S,17S)-3-methoxy-13-methyl-17-(tetrahydro-pyran-2-yloxy)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-16-ylmethyl ester

Synonyms:Toluene-4-sulfonic acid (8R,9S,13R,14S,16S,17S)-3-methoxy-13-methyl-17-(tetrahydro-pyran-2-yloxy)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-16-ylmethyl ester

Suppliers and Price of Toluene-4-sulfonic acid (8R,9S,13R,14S,16S,17S)-3-methoxy-13-methyl-17-(tetrahydro-pyran-2-yloxy)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-16-ylmethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Toluene-4-sulfonic acid (8R,9S,13R,14S,16S,17S)-3-methoxy-13-methyl-17-(tetrahydro-pyran-2-yloxy)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-16-ylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Toluene-4-sulfonic acid (8R,9S,13R,14S,16S,17S)-3-methoxy-13-methyl-17-(tetrahydro-pyran-2-yloxy)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-16-ylmethyl ester

There total 3 articles about Toluene-4-sulfonic acid (8R,9S,13R,14S,16S,17S)-3-methoxy-13-methyl-17-(tetrahydro-pyran-2-yloxy)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-16-ylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 110-87-2
3,4-dihydro-2H-pyran

: 618457-29-7
16α-toluene-p-sulfonyloxymethyl-3-methoxy-13α-estra-1,3,5(10)-trien-17β-ol

: 618457-34-4
Toluene-4-sulfonic acid (8R,9S,13R,14S,16S,17S)-3-methoxy-13-methyl-17-(tetrahydro-pyran-2-yloxy)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-16-ylmethyl ester

Guidance literature:: With p-toluenesulfonyl chloride; In dichloromethane; at 20 ℃; for 1h;
DOI:10.1016/S0039-128X(03)00048-5

Reference yield:

: 98-59-9
p-toluenesulfonyl chloride

: 618457-34-4
Toluene-4-sulfonic acid (8R,9S,13R,14S,16S,17S)-3-methoxy-13-methyl-17-(tetrahydro-pyran-2-yloxy)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-16-ylmethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: KBH₄ / methanol / 4 h / 20 °C

1.2: 70 percent / pyridine / 24 h

2.1: 90 percent / p-toluenesulfonyl chloride / CH₂Cl₂ / 1 h / 20 °C

With potassium borohydride; p-toluenesulfonyl chloride; In methanol; dichloromethane;
DOI:10.1016/S0039-128X(03)00048-5

Reference yield:

: 16-hydroxymethylene-3-methoxy-13α-estra-1,3,5(10)-trien-17-one

: 618457-34-4
Toluene-4-sulfonic acid (8R,9S,13R,14S,16S,17S)-3-methoxy-13-methyl-17-(tetrahydro-pyran-2-yloxy)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-16-ylmethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: KBH₄ / methanol / 4 h / 20 °C

1.2: 70 percent / pyridine / 24 h

2.1: 90 percent / p-toluenesulfonyl chloride / CH₂Cl₂ / 1 h / 20 °C

With potassium borohydride; p-toluenesulfonyl chloride; In methanol; dichloromethane;
DOI:10.1016/S0039-128X(03)00048-5