6-(2-Fluorophenyl)imidazo[2,1-b][1,3]thiazole

Base Information

Chemical Name:6-(2-Fluorophenyl)imidazo[2,1-b][1,3]thiazole
CAS No.:439094-75-4
Molecular Formula:C₁₁H₇FN₂S
Molecular Weight:218.254
Hs Code.:
DSSTox Substance ID:DTXSID301273912
ChEMBL ID:CHEMBL1910341

Synonyms:6-(2-fluorophenyl)imidazo[2,1-b][1,3]thiazole;439094-75-4;6-(2-fluorophenyl)imidazo[2,1-b]thiazole;Bionet2_001324;CHEMBL1910341;DTXSID301273912;HMS1367M04;MFCD00973878;AKOS005081364;12R-0262

Suppliers and Price of 6-(2-Fluorophenyl)imidazo[2,1-b][1,3]thiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 6-(2-Fluorophenyl)imidazo[2,1-b][1,3]thiazole

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:218.03139757
Heavy Atom Count:15
Complexity:239

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C2=CN3C=CSC3=N2)F

Technology Process of 6-(2-Fluorophenyl)imidazo[2,1-b][1,3]thiazole

There total 1 articles about 6-(2-Fluorophenyl)imidazo[2,1-b][1,3]thiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 655-15-2
2-bromo-2'-fluoroacetophenone

: 96-50-4
2-amino-thiazole

: 439094-75-4
C₁₁H₇FN₂S

Guidance literature:: 2-bromo-2'-fluoroacetophenone; 2-amino-thiazole; In acetone; Reflux;

With hydrogenchloride; In water; Reflux;

With ammonium hydroxide; In water;
DOI:10.1016/j.ejmech.2011.07.001

Reference yield:

: 439094-75-4
C₁₁H₇FN₂S

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 439095-02-0
C₁₂H₇FN₂OS

Guidance literature:: N,N-dimethyl-formamide; With trichlorophosphate; In chloroform; at 0 - 5 ℃;

C₁₁H₇FN₂S; In chloroform; Cooling; Reflux;
DOI:10.1016/j.ejmech.2011.07.001

Reference yield:

: 439094-75-4
C₁₁H₇FN₂S

: 1336804-55-7
NSC 747415

Guidance literature:: Multi-step reaction with 2 steps

1.1: trichlorophosphate / chloroform / 0 - 5 °C

1.2: Cooling; Reflux

2.1: ethanol / Reflux

With trichlorophosphate; In ethanol; chloroform; 1.1: Vilsmeier reaction / 1.2: Vilsmeier reaction;
DOI:10.1016/j.ejmech.2011.07.001