tert-butyl-(((3S,4R,Z)-4,5-dimethyl-7-(trityloxy)hepta-1,5-dien-3-yl)oxy)dimethylsilane

Base Information

Chemical Name:tert-butyl-(((3S,4R,Z)-4,5-dimethyl-7-(trityloxy)hepta-1,5-dien-3-yl)oxy)dimethylsilane
CAS No.:1322574-58-2
Molecular Formula:C₃₄H₄₄O₂Si
Molecular Weight:512.808
Hs Code.:

Synonyms:tert-butyl-(((3S,4R,Z)-4,5-dimethyl-7-(trityloxy)hepta-1,5-dien-3-yl)oxy)dimethylsilane

Suppliers and Price of tert-butyl-(((3S,4R,Z)-4,5-dimethyl-7-(trityloxy)hepta-1,5-dien-3-yl)oxy)dimethylsilane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of tert-butyl-(((3S,4R,Z)-4,5-dimethyl-7-(trityloxy)hepta-1,5-dien-3-yl)oxy)dimethylsilane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyl-(((3S,4R,Z)-4,5-dimethyl-7-(trityloxy)hepta-1,5-dien-3-yl)oxy)dimethylsilane

There total 11 articles about tert-butyl-(((3S,4R,Z)-4,5-dimethyl-7-(trityloxy)hepta-1,5-dien-3-yl)oxy)dimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 1322574-79-7
C₃₄H₄₅IO₂Si

: 1322574-58-2
tert-butyl-(((3S,4R,Z)-4,5-dimethyl-7-(trityloxy)hepta-1,5-dien-3-yl)oxy)dimethylsilane

Guidance literature:: With potassium tert-butylate; In tetrahydrofuran; at 0 ℃; for 5h; Inert atmosphere;
DOI:10.1016/j.tet.2011.06.025

Reference yield:

: 1322574-74-2
C₂₆H₃₄O₃Si

: 1322574-58-2
tert-butyl-(((3S,4R,Z)-4,5-dimethyl-7-(trityloxy)hepta-1,5-dien-3-yl)oxy)dimethylsilane

Guidance literature:: Multi-step reaction with 10 steps

1.1: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 12 h / Inert atmosphere; Reflux

2.1: copper(l) iodide / diethyl ether / 0.33 h / 0 °C / Inert atmosphere

2.2: 5 h / 0 °C / Inert atmosphere

2.3: Inert atmosphere

3.1: lithium diisopropyl amide / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere

3.2: 0.5 h / -78 °C / Inert atmosphere

4.1: sodium tetrahydroborate; cerium(III) chloride heptahydrate / methanol / 3 h / 0 °C / Inert atmosphere

5.1: dmap; triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere

6.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / 20 °C / Inert atmosphere

6.2: 20 °C / Inert atmosphere

7.1: dmap; triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere

8.1: 2,6-dimethylpyridine / dichloromethane / 1 h / 0 °C / Inert atmosphere

9.1: sodium iodide / acetone / 48 h / 20 °C / Inert atmosphere

10.1: potassium tert-butylate / tetrahydrofuran / 5 h / 0 °C / Inert atmosphere

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; 2,6-dimethylpyridine; dmap; sodium tetrahydroborate; copper(l) iodide; cerium(III) chloride heptahydrate; potassium tert-butylate; tetrabutyl ammonium fluoride; triethylamine; sodium iodide; lithium diisopropyl amide; In tetrahydrofuran; methanol; diethyl ether; hexane; dichloromethane; acetone;
DOI:10.1016/j.tet.2011.06.025

Reference yield:

: 1322574-54-8
(5R,6S)-6-(2-((tert-butyldiphenylsilyl)oxy)ethyl)-5-methyl-5,6-dihydro-2H-pyran-2-one

: 1322574-58-2
tert-butyl-(((3S,4R,Z)-4,5-dimethyl-7-(trityloxy)hepta-1,5-dien-3-yl)oxy)dimethylsilane

Guidance literature:: Multi-step reaction with 9 steps

1.1: copper(l) iodide / diethyl ether / 0.33 h / 0 °C / Inert atmosphere

1.2: 5 h / 0 °C / Inert atmosphere

1.3: Inert atmosphere

2.1: lithium diisopropyl amide / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere

2.2: 0.5 h / -78 °C / Inert atmosphere

3.1: sodium tetrahydroborate; cerium(III) chloride heptahydrate / methanol / 3 h / 0 °C / Inert atmosphere

4.1: dmap; triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere

5.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / 20 °C / Inert atmosphere

5.2: 20 °C / Inert atmosphere

6.1: dmap; triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere

7.1: 2,6-dimethylpyridine / dichloromethane / 1 h / 0 °C / Inert atmosphere

8.1: sodium iodide / acetone / 48 h / 20 °C / Inert atmosphere

9.1: potassium tert-butylate / tetrahydrofuran / 5 h / 0 °C / Inert atmosphere

With 2,6-dimethylpyridine; dmap; sodium tetrahydroborate; copper(l) iodide; cerium(III) chloride heptahydrate; potassium tert-butylate; tetrabutyl ammonium fluoride; triethylamine; sodium iodide; lithium diisopropyl amide; In tetrahydrofuran; methanol; diethyl ether; hexane; dichloromethane; acetone;
DOI:10.1016/j.tet.2011.06.025