10-[(S)-1-(1-phenyl)ethylcarbamoylmethyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triyltrimethylene(methylphosphinic acid)

Base Information

Chemical Name:10-[(S)-1-(1-phenyl)ethylcarbamoylmethyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triyltrimethylene(methylphosphinic acid)
CAS No.:204252-92-6
Molecular Formula:C₂₄H₄₆N₅O₇P₃
Molecular Weight:609.58
Hs Code.:

Synonyms:10-[(S)-1-(1-phenyl)ethylcarbamoylmethyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triyltrimethylene(methylphosphinic acid)

Suppliers and Price of 10-[(S)-1-(1-phenyl)ethylcarbamoylmethyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triyltrimethylene(methylphosphinic acid)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 10-[(S)-1-(1-phenyl)ethylcarbamoylmethyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triyltrimethylene(methylphosphinic acid)

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 10-[(S)-1-(1-phenyl)ethylcarbamoylmethyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triyltrimethylene(methylphosphinic acid)

There total 4 articles about 10-[(S)-1-(1-phenyl)ethylcarbamoylmethyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triyltrimethylene(methylphosphinic acid) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 204925-49-5
{4,10-Bis-(ethoxy-methyl-phosphinoylmethyl)-7-[((S)-1-phenyl-ethylcarbamoyl)-methyl]-1,4,7,10-tetraaza-cyclododec-1-ylmethyl}-methyl-phosphinic acid ethyl ester

: 204252-92-6
10-[(S)-1-(1-phenyl)ethylcarbamoylmethyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triyltrimethylene(methylphosphinic acid)

Guidance literature:: With potassium hydroxide; In water; for 18h; Ambient temperature;
DOI:10.1039/a708667i

Reference yield:

: 2627-86-3
(S)-1-phenyl-ethylamine

: 204252-92-6
10-[(S)-1-(1-phenyl)ethylcarbamoylmethyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triyltrimethylene(methylphosphinic acid)

Guidance literature:: Multi-step reaction with 4 steps

1: 60 percent / Et₃N / diethyl ether / -20 deg C then r.t., 1 h

2: 2.) K₂CO₃ / 1.) Bu₂O, reflux, 2 h; 2.) DMF, 60 deg C, 4 h

3: 55 percent / tetrahydrofuran; diethyl ether / 18.5 h / Heating

4: 82 percent / KOH / H₂O / 18 h / Ambient temperature

With potassium hydroxide; potassium carbonate; triethylamine; In tetrahydrofuran; diethyl ether; water;
DOI:10.1039/a708667i

Reference yield:

: 36293-01-3
2-chloro-N-((1S)-1-phenylethyl)acetamide

: 204252-92-6
10-[(S)-1-(1-phenyl)ethylcarbamoylmethyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triyltrimethylene(methylphosphinic acid)

Guidance literature:: Multi-step reaction with 3 steps

1: 2.) K₂CO₃ / 1.) Bu₂O, reflux, 2 h; 2.) DMF, 60 deg C, 4 h

2: 55 percent / tetrahydrofuran; diethyl ether / 18.5 h / Heating

3: 82 percent / KOH / H₂O / 18 h / Ambient temperature

With potassium hydroxide; potassium carbonate; In tetrahydrofuran; diethyl ether; water;
DOI:10.1039/a708667i