(R,E)-benzyl {4-[4-(heptyloxy)phenyl]-2-methyl-2-nitrobut-3-en-1-yl} carbonate

Base Information

• Chemical Name: (R,E)-benzyl {4-[4-(heptyloxy)phenyl]-2-methyl-2-nitrobut-3-en-1-yl} carbonate
• CAS No.: 1330530-16-9
• Molecular Formula: C₂₆H₃₃NO₆
• Molecular Weight: 455.551
• Mol file: 1330530-16-9.mol

Synonyms:(R,E)-benzyl {4-[4-(heptyloxy)phenyl]-2-methyl-2-nitrobut-3-en-1-yl} carbonate

Chemical Property of (R,E)-benzyl {4-[4-(heptyloxy)phenyl]-2-methyl-2-nitrobut-3-en-1-yl} carbonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R,E)-benzyl {4-[4-(heptyloxy)phenyl]-2-methyl-2-nitrobut-3-en-1-yl} carbonate

There total 1 articles about (R,E)-benzyl {4-[4-(heptyloxy)phenyl]-2-methyl-2-nitrobut-3-en-1-yl} carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

p-C7H15OC6H4N2BF4 + (R)-benzyl (2-methyl-2-nitrobut-3-en-1-yl) carbonate (1330530-15-8) → (R,E)-benzyl {4-[4-(heptyloxy)phenyl]-2-methyl-2-nitrobut-3-en-1-yl} carbonate (1330530-16-9)

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; sodium acetate; In acetonitrile; at 20 ℃; for 48h; Inert atmosphere;

DOI:10.1002/ejoc.201101703

Reference yield: 97.0%

(R,E)-benzyl {4-[4-(heptyloxy)phenyl]-2-methyl-2-nitrobut-3-en-1-yl} carbonate (1330530-16-9) → (2R)-2-amino-4-[4-(heptyloxy)phenyl]-2-methylbutan-1-ol (241476-71-1)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 50h; under 37503.8 Torr;

DOI:10.1002/ejoc.201101703

upstream raw materials:

(R)-benzyl (2-methyl-2-nitrobut-3-en-1-yl) carbonate

Downstream raw materials:

(2R)-2-amino-4-[4-(heptyloxy)phenyl]-2-methylbutan-1-ol