methyl (4-methoxyphenyl)[4-(trifluoromethyl)phenyl]methyl carbonate

Base Information

• Chemical Name: methyl (4-methoxyphenyl)[4-(trifluoromethyl)phenyl]methyl carbonate
• CAS No.: 1012862-97-3
• Molecular Formula: C₁₇H₁₅F₃O₄
• Molecular Weight: 340.299
• Mol file: 1012862-97-3.mol

Synonyms:methyl (4-methoxyphenyl)[4-(trifluoromethyl)phenyl]methyl carbonate

Chemical Property of methyl (4-methoxyphenyl)[4-(trifluoromethyl)phenyl]methyl carbonate

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of methyl (4-methoxyphenyl)[4-(trifluoromethyl)phenyl]methyl carbonate

There total 1 articles about methyl (4-methoxyphenyl)[4-(trifluoromethyl)phenyl]methyl carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

α-(4-methoxyphenyl)(4-trifluoromethyl)benzyl alcohol (87901-71-1) + methyl chloroformate (79-22-1) → methyl (4-methoxyphenyl)[4-(trifluoromethyl)phenyl]methyl carbonate (1012862-97-3)

Guidance literature:

With pyridine; dmap; In dichloromethane; at 0 - 20 ℃; for 8h;

DOI:10.1021/ol800078j

Reference yield: 77.0%

methyl (4-methoxyphenyl)[4-(trifluoromethyl)phenyl]methyl carbonate (1012862-97-3) + phenylboronic acid (98-80-6) → (4-methoxyphenyl)phenyl[4-(trifluoromethyl)phenyl]methane (1012863-17-0)

Guidance literature:

With bis(η3-allyl-μ-chloropalladium(II)); 1,5-bis-(diphenylphosphino)pentane; potassium carbonate; In tert-Amyl alcohol; at 100 ℃; for 72h; Inert atmosphere;

DOI:10.1021/ol800078j

upstream raw materials:

α-(4-methoxyphenyl)(4-trifluoromethyl)benzyl alcohol

methyl chloroformate

Downstream raw materials:

(4-methoxyphenyl)phenyl[4-(trifluoromethyl)phenyl]methane