11-benzyl-4,4α,5,11,11bα-hexahydro-1H-benzocarbazole-1,4-dione

Base Information

• Chemical Name: 11-benzyl-4,4α,5,11,11bα-hexahydro-1H-benzo
• Molecular Formula: C₂₃H₁₉NO₂
• Molecular Weight: 341.409

Synonyms:11-benzyl-4,4α,5,11,11bα-hexahydro-1H-benzocarbazole-1,4-dione

Chemical Property of 11-benzyl-4,4α,5,11,11bα-hexahydro-1H-benzo

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

There total 3 articles about 11-benzyl-4,4α,5,11,11bα-hexahydro-1H-benzocarbazole-1,4-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

1-benzyl-3-vinyl-1H-indole (79670-21-6) + p-benzoquinone (106-51-4) → 11-benzyl-4,4α,5,11,11bα-hexahydro-1H-benzocarbazole-1,4-dione (79670-22-7)

Guidance literature:

In ethanol; for 1h;

Reference yield:

1-Benzylindole-3-carboxaldehyde (10511-51-0) → 11-benzyl-4,4α,5,11,11bα-hexahydro-1H-benzocarbazole-1,4-dione (79670-22-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 83 percent / dimethylsulfoxide / 4 h

2: 86 percent / ethanol / 1 h

In ethanol; dimethyl sulfoxide;

Reference yield:

Indole-3-carboxaldehyde (487-89-8,1228547-52-1) → 11-benzyl-4,4α,5,11,11bα-hexahydro-1H-benzocarbazole-1,4-dione (79670-22-7)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate / dichloromethane / 0.5 h / 20 °C / Inert atmosphere

1.2: 5 h / Inert atmosphere

2.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -30 °C / Inert atmosphere

2.2: 1 h / -30 °C / Inert atmosphere

3.1: 2C₅₀H₅₆O₄P^(1-)*Mg⁽²⁺⁾ / methyl cyclohexane / -25 °C / Molecular sieve; Inert atmosphere

With n-butyllithium; 2C₅₀H₅₆O₄P^(1-)*Mg⁽²⁺⁾; tetra(n-butyl)ammonium hydrogensulfate; sodium hydroxide; In tetrahydrofuran; hexane; dichloromethane; methyl cyclohexane; 2.1: |Wittig Olefination / 2.2: |Wittig Olefination / 3.1: |Diels-Alder Cycloaddition;

DOI:10.1021/acs.orglett.9b01437

upstream raw materials:

1-benzyl-3-vinyl-1H-indole

p-benzoquinone

1-Benzylindole-3-carboxaldehyde

Indole-3-carboxaldehyde

Downstream raw materials:

11-benzyl-1H-benzocarbazole-1,4-quinone

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 79670-22-7 11-benzyl-4,4α,5,11,11bα-hexahydro-1H-benzocarbazole-1,4-dione

Send

Send

Metric Ton KG G Pound L ML

Send

Send