1-[(4-Fluorophenyl)sulfonyl]-3-piperidinamine

Base Information

Chemical Name:1-[(4-Fluorophenyl)sulfonyl]-3-piperidinamine
CAS No.:1016538-91-2
Molecular Formula:C₁₁H₁₅FN₂O₂S
Molecular Weight:258.317
Hs Code.:
DSSTox Substance ID:DTXSID501255067

Synonyms:SCHEMBL22868370;DTXSID501255067;AKOS000224924;1016538-91-2;1-[(4-Fluorophenyl)sulfonyl]-3-piperidinamine

Suppliers and Price of 1-[(4-Fluorophenyl)sulfonyl]-3-piperidinamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1-[(4-Fluorophenyl)sulfonyl]-3-piperidinamine

Chemical Property:

XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:258.08382706
Heavy Atom Count:17
Complexity:347

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC(CN(C1)S(=O)(=O)C2=CC=C(C=C2)F)N

Technology Process of 1-[(4-Fluorophenyl)sulfonyl]-3-piperidinamine

There total 3 articles about 1-[(4-Fluorophenyl)sulfonyl]-3-piperidinamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 1016539-02-8
1-((4-fluorophenyl)sulfonyl)piperidin-3-one

: 1016538-91-2
N-(4-fluorophenylsulfonyl)piperidin-3-amine

Guidance literature:: With ammonium acetate; sodium cyanoborohydride; In methanol; at 20 ℃; for 48h;
DOI:10.1016/j.bmc.2007.10.050

Reference yield:

: 184637-48-7,172603-05-3
t-butyl piperidin-3-ylcarbamate

: 1016538-91-2
N-(4-fluorophenylsulfonyl)piperidin-3-amine

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 0 °C

2: hydrogenchloride / dichloromethane; water / 40 °C

With hydrogenchloride; triethylamine; In dichloromethane; water;