C₄₀H₅₇N₉O₁₂S

Base Information

• Chemical Name: C₄₀H₅₇N₉O₁₂S
• CAS No.: 1389332-52-8
• Molecular Formula: C₄₀H₅₇N₉O₁₂S
• Molecular Weight: 888.012
• Mol file: 1389332-52-8.mol

Synonyms:C₄₀H₅₇N₉O₁₂S

Chemical Property of C₄₀H₅₇N₉O₁₂S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₀H₅₇N₉O₁₂S

There total 7 articles about C₄₀H₅₇N₉O₁₂S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C55H69N9O14S (1389332-47-1) → C40H57N9O12S (1389332-52-8)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In tetrahydrofuran; water; at 20 ℃; under 750.075 Torr; Inert atmosphere;

DOI:10.1002/chem.201200457

Reference yield:

C15H19N3O4 (1389332-32-4) → C40H57N9O12S (1389332-52-8)

Guidance literature:

Multi-step reaction with 6 steps

1.1: tetrahydrofuran / 20 °C / Inert atmosphere

2.1: lithium hydroxide monohydrate / tetrahydrofuran; water / 1 h / 0 °C / Inert atmosphere

3.1: 1-hydroxy-7-aza-benzotriazole; N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 0.5 h / 0 °C / Inert atmosphere

3.2: 0 - 20 °C / Inert atmosphere

4.1: dichloromethane / 2 h / 20 °C / Inert atmosphere

5.1: 1-hydroxy-7-aza-benzotriazole; N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 0.5 h / 0 °C / Inert atmosphere

5.2: 0 - 20 °C / Inert atmosphere

6.1: palladium 10% on activated carbon; hydrogen / tetrahydrofuran; water / 20 °C / 750.08 Torr / Inert atmosphere

With 1-hydroxy-7-aza-benzotriazole; lithium hydroxide monohydrate; palladium 10% on activated carbon; hydrogen; N-ethyl-N,N-diisopropylamine; HATU; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide;

DOI:10.1002/chem.201200457

Reference yield:

C2HF3O2*C16H21N5O5 → C40H57N9O12S (1389332-52-8)

Guidance literature:

Multi-step reaction with 8 steps

1.1: N-ethyl-N,N-diisopropylamine / isopropyl alcohol / 5 h / 20 °C / Inert atmosphere

2.1: palladium on activated charcoal; hydrogen / tetrahydrofuran / 4 h / 20 °C / Inert atmosphere

3.1: tetrahydrofuran / 20 °C / Inert atmosphere

4.1: lithium hydroxide monohydrate / tetrahydrofuran; water / 1 h / 0 °C / Inert atmosphere

5.1: 1-hydroxy-7-aza-benzotriazole; N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 0.5 h / 0 °C / Inert atmosphere

5.2: 0 - 20 °C / Inert atmosphere

6.1: dichloromethane / 2 h / 20 °C / Inert atmosphere

7.1: 1-hydroxy-7-aza-benzotriazole; N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 0.5 h / 0 °C / Inert atmosphere

7.2: 0 - 20 °C / Inert atmosphere

8.1: palladium 10% on activated carbon; hydrogen / tetrahydrofuran; water / 20 °C / 750.08 Torr / Inert atmosphere

With 1-hydroxy-7-aza-benzotriazole; lithium hydroxide monohydrate; palladium on activated charcoal; palladium 10% on activated carbon; hydrogen; N-ethyl-N,N-diisopropylamine; HATU; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; isopropyl alcohol;

DOI:10.1002/chem.201200457

upstream raw materials:

C₂₁H₂₉N₅O₇

C₁₅H₁₇N₅O₄

C₁₅H₁₉N₃O₄

C₂₀H₂₇N₃O₆

Downstream raw materials:

C₄₀H₅₅N₉O₁₁S

C₂HF₃O₂*C₂₆H₃₅N₉O₈