trans-(3-t-butyl-3,3-diphenyl-1,1-dimethyldisiloxy)methyl-4-ethyl-1,1-bis(trimethylacetoxymethyl)cyclopentane

Base Information

• Chemical Name: trans-(3-t-butyl-3,3-diphenyl-1,1-dimethyldisiloxy)methyl-4-ethyl-1,1-bis(trimethylacetoxymethyl)cyclopentane
• CAS No.: 315191-34-5
• Molecular Formula: C₃₈H₆₀O₅Si₂
• Molecular Weight: 653.062
• Mol file: 315191-34-5.mol

Synonyms:trans-(3-t-butyl-3,3-diphenyl-1,1-dimethyldisiloxy)methyl-4-ethyl-1,1-bis(trimethylacetoxymethyl)cyclopentane

Chemical Property of trans-(3-t-butyl-3,3-diphenyl-1,1-dimethyldisiloxy)methyl-4-ethyl-1,1-bis(trimethylacetoxymethyl)cyclopentane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-(3-t-butyl-3,3-diphenyl-1,1-dimethyldisiloxy)methyl-4-ethyl-1,1-bis(trimethylacetoxymethyl)cyclopentane

There total 2 articles about trans-(3-t-butyl-3,3-diphenyl-1,1-dimethyldisiloxy)methyl-4-ethyl-1,1-bis(trimethylacetoxymethyl)cyclopentane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-tert-butyl-3,3-dimethyl-1,1-diphenyldisiloxane (315191-15-2) + 2,2-Dimethyl-propionic acid (E)-2-allyl-2-(2,2-dimethyl-propionyloxymethyl)-hex-4-enyl ester → 2,2-Dimethyl-propionic acid (3R,4R)-3-(3-tert-butyl-1,1-dimethyl-3,3-diphenyl-disiloxanylmethyl)-1-(2,2-dimethyl-propionyloxymethyl)-4-ethyl-cyclopentylmethyl ester + trans-(3-t-butyl-3,3-diphenyl-1,1-dimethyldisiloxy)methyl-4-ethyl-1,1-bis(trimethylacetoxymethyl)cyclopentane (315191-34-5)

Guidance literature:

With [(R)-(+)-4-isopropyl-2-(2-pyridinyl)-2-oxazoline]Pd(Me)Cl; sodium tetrakis[(3,5-di-trifluoromethyl)phenyl]borate; In dichloromethane; at -20 ℃; for 12h; Title compound not separated from byproducts;

DOI:10.1016/S0040-4039(00)01321-6

Reference yield:

tert-butylchlorodiphenylsilane (58479-61-1) → trans-(3-t-butyl-3,3-diphenyl-1,1-dimethyldisiloxy)methyl-4-ethyl-1,1-bis(trimethylacetoxymethyl)cyclopentane (315191-34-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent / NaHCO₃ / H₂O; tetrahydrofuran / 0 - 20 °C

2: [(R)-(+)-4-isopropyl-2-(2-pyridinyl)-2-oxazoline]Pd(Me)Cl; NaB[3,5-C₆H₃(CF₃)2]4 / CH₂Cl₂ / 12 h / -20 °C

With [(R)-(+)-4-isopropyl-2-(2-pyridinyl)-2-oxazoline]Pd(Me)Cl; sodium hydrogencarbonate; sodium tetrakis[(3,5-di-trifluoromethyl)phenyl]borate; In tetrahydrofuran; dichloromethane; water;

DOI:10.1021/jo015724n

upstream raw materials:

1-tert-butyl-3,3-dimethyl-1,1-diphenyldisiloxane

tert-butylchlorodiphenylsilane