C₃₅H₄₈OSi

Base Information

• Chemical Name: C₃₅H₄₈OSi
• CAS No.: 1618098-60-4
• Molecular Formula: C₃₅H₄₈OSi
• Molecular Weight: 512.851
• Mol file: 1618098-60-4.mol

Synonyms:C₃₅H₄₈OSi

Chemical Property of C₃₅H₄₈OSi

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₅H₄₈OSi

There total 13 articles about C₃₅H₄₈OSi which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

C42H56N2O3SSi → C35H48OSi (1618098-60-4)

Guidance literature:

With sodium hydride; In toluene; mineral oil; at 0 - 110 ℃; stereoselective reaction; Inert atmosphere;

DOI:10.1021/ja5054412

Reference yield:

C17H28O2 → C35H48OSi (1618098-60-4)

Guidance literature:

Multi-step reaction with 9 steps

1.1: lithium aluminium tetrahydride / diethyl ether / 0 - 20 °C

2.1: diethyl (2S,3S)-tartrate; titanium(IV) isopropylate; tert.-butylhydroperoxide / dichloromethane; decane / 8 h / -30 °C / Molecular sieve

3.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.25 h / -78 °C

3.2: -78 - 20 °C

4.1: potassium carbonate / methanol / 20 °C

5.1: magnesium; ethylene dibromide / tetrahydrofuran / 1 h / 20 °C

5.2: 1 h / -15 °C

6.1: 1H-imidazole; dmap / dichloromethane / 0 - 20 °C

7.1: toluene-4-sulfonic acid; formaldehyd / tetrahydrofuran; water / 36 h / 20 °C

8.1: methanol / 3 h / 0 - 20 °C

9.1: sodium hydride / toluene; mineral oil / 0 - 110 °C / Inert atmosphere

With 1H-imidazole; titanium(IV) isopropylate; tert.-butylhydroperoxide; dmap; lithium aluminium tetrahydride; formaldehyd; oxalyl dichloride; diethyl (2S,3S)-tartrate; sodium hydride; potassium carbonate; toluene-4-sulfonic acid; magnesium; dimethyl sulfoxide; ethylene dibromide; In tetrahydrofuran; methanol; diethyl ether; decane; dichloromethane; water; toluene; mineral oil; 2.1: |Sharpless Asymmetric Epoxidation / 3.1: |Swern Oxidation / 3.2: |Swern Oxidation;

DOI:10.1021/ja5054412

Reference yield:

C21H36O3 → C35H48OSi (1618098-60-4)

Guidance literature:

Multi-step reaction with 4 steps

1: 1H-imidazole; dmap / dichloromethane / 0 - 20 °C

2: toluene-4-sulfonic acid; formaldehyd / tetrahydrofuran; water / 36 h / 20 °C

3: methanol / 3 h / 0 - 20 °C

4: sodium hydride / toluene; mineral oil / 0 - 110 °C / Inert atmosphere

With 1H-imidazole; dmap; formaldehyd; sodium hydride; toluene-4-sulfonic acid; In tetrahydrofuran; methanol; dichloromethane; water; toluene; mineral oil;

DOI:10.1021/ja5054412

upstream raw materials:

C₁₈H₃₆OSi

C₁₅H₂₄O₂

C₁₂H₂₂O

C₁₅H₂₆O₂

Downstream raw materials:

(-)-crinipellin A