benzhydryl 4-(trifluoromethyl)benzoate

Base Information

• Chemical Name: benzhydryl 4-(trifluoromethyl)benzoate
• CAS No.: 53914-66-2
• Molecular Formula: C₂₁H₁₅F₃O₂
• Molecular Weight: 356.344
• Mol file: 53914-66-2.mol

Synonyms:benzhydryl 4-(trifluoromethyl)benzoate

Chemical Property of benzhydryl 4-(trifluoromethyl)benzoate

Chemical Property:

Purity/Quality:

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Technology Process of benzhydryl 4-(trifluoromethyl)benzoate

There total 2 articles about benzhydryl 4-(trifluoromethyl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

1,1-Diphenylmethanol (91-01-0) + 4-trifluoromethyl-phenyl acetyl chloride (329-15-7) → benzhydryl 4-(trifluoromethyl)benzoate (53914-66-2)

Guidance literature:

With dmap; triethylamine; In dichloromethane; at 0 - 20 ℃; Schlenk technique;

DOI:10.3762/bjoc.10.223

Reference yield:

→ benzhydryl 4-(trifluoromethyl)benzoate (53914-66-2)

Guidance literature:

Benzhydrol + Benzoylchlorid in Pyridin;

DOI:10.1021/ja00821a022

upstream raw materials:

1,1-Diphenylmethanol

4-trifluoromethyl-phenyl acetyl chloride

Refernces