7-(4-Methoxy-phenyl)-5-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-ylamine

Base Information

• Chemical Name: 7-(4-Methoxy-phenyl)-5-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-ylamine
• CAS No.: 134834-78-9
• Molecular Formula: C₁₈H₁₇N₅O
• Molecular Weight: 319.366
• Mol file: 134834-78-9.mol

Synonyms:7-(4-Methoxy-phenyl)-5-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-ylamine

Chemical Property of 7-(4-Methoxy-phenyl)-5-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-ylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7-(4-Methoxy-phenyl)-5-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-ylamine

There total 2 articles about 7-(4-Methoxy-phenyl)-5-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-ylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

guanazole (1455-77-2) + 3-(4-methoxyphenyl)-1-phenylprop-2-en-1-one (959-33-1) → 7-(4-Methoxy-phenyl)-5-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-ylamine (134834-78-9)

Guidance literature:

In N,N-dimethyl-formamide; for 0.5h; Heating;

DOI:10.1007/BF02218988

Reference yield: 5.0%

guanazole (1455-77-2) + 3-(4-methoxyphenyl)-1-phenylprop-2-en-1-one (959-33-1) → 7-(4-Methoxy-phenyl)-5-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-ylamine (134834-73-4) + 7-(4-Methoxy-phenyl)-5-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-ylamine (134834-78-9)

Guidance literature:

In N,N-dimethyl-formamide; Heating;

DOI:10.1007/BF00509707

Reference yield: 91.0%

7-(4-Methoxy-phenyl)-5-phenyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-ylamine (134834-78-9) + p-toluenesulfonyl chloride (98-59-9) → 7-(4-methoxyphenyl)-2-(p-toluenesulfonylamino)-5-phenyl-4,5,6,7-tetrahydro-1,2,4-triazolo[1,5-a]pyrimidine (1123816-46-5)

Guidance literature:

With pyridine; for 0.0833333h; Reflux;

DOI:10.1134/S107042800805014X

upstream raw materials:

guanazole

3-(4-methoxyphenyl)-1-phenylprop-2-en-1-one

Downstream raw materials:

7-(4-Methoxy-phenyl)-5-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-ylamine

C₂₀H₁₉N₅O₂

C₂₀H₁₇N₅O₂

7-(4-methoxyphenyl)-2-(p-toluenesulfonylamino)-5-phenyl-4,5,6,7-tetrahydro-1,2,4-triazolo[1,5-a]pyrimidine