Chemical Property of Monazomycin A
Chemical Property:
- Vapor Pressure:0mmHg at 25°C
- Melting Point:127°C
- Refractive Index:1.5280 (estimate)
- Boiling Point:1327.1°Cat760mmHg
- PKA:12.89±0.70(Predicted)
- Flash Point:756.4°C
- PSA：434.92000
- Density:1.22g/cm3
- LogP:4.19630
- Solubility.:Soluble in DMSO
- XLogP3:4.3
- Hydrogen Bond Donor Count:19
- Hydrogen Bond Acceptor Count:23
- Rotatable Bond Count:10
- Exact Mass:1363.93192487
- Heavy Atom Count:95
- Complexity:2190
- Purity/Quality:
-
98%,99%, *data from raw suppliers
Monazomycin ≥95% *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
- Canonical SMILES:CC1CCC(CC(C(C(C(C(CC(CC(C(C(OC(=O)CCCCCC(C(C(CCC=CC(C(C(=CC(C(C(=CC(C(C(C(CC(C=CC(C1O)C)O)O)C)O)OC2C(C(C(C(O2)CO)O)O)O)C)O)C)C)O)C)O)C)O)C(C)CCCCCCN)C)O)O)O)C)O)C)O)O
- Isomeric SMILES:CC1CCC(CC(C(C(C(C(CC(CC(C(C(OC(=O)CCCCCC(C(C(CC/C=C/C(C(/C(=C/C(C(/C(=C/C(C(C(C(CC(/C=C/C(C1O)C)O)O)C)O)OC2C(C(C(C(O2)CO)O)O)O)/C)O)C)/C)O)C)O)C)O)C(C)CCCCCCN)C)O)O)O)C)O)C)O)O
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Uses
Monazomycin is a macrocylic polyol lactone isolated from several species of Streptoverticillium, first reported in 1963. Monazomycin is active against Gram positive bacteria with weak Gram negative activity. In solution, monazomycin exists as hydrophilic clusters which, when adsorbed onto a lipid bilayer, can induce channel formation. Monazomycin is an important bioprobe for understanding membrane channels. Monazomycin is a macrocyclic polyol lactone antibiotic isolated from Streptoverticilium.
