C₄₅H₅₆N₆O₆

Base Information

• Chemical Name: C₄₅H₅₆N₆O₆
• CAS No.: 1004519-75-8
• Molecular Formula: C₄₅H₅₆N₆O₆
• Molecular Weight: 776.976
• Mol file: 1004519-75-8.mol

Synonyms:C₄₅H₅₆N₆O₆

Chemical Property of C₄₅H₅₆N₆O₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₅H₅₆N₆O₆

There total 3 articles about C₄₅H₅₆N₆O₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

methyl 3,7,12-trideoxy-3α,12α-bis(2-azidoacetyloxy)cholate (1002095-40-0) + phenylacetylene (536-74-3) → C45H56N6O6 (1004519-75-8)

Guidance literature:

With copper(l) iodide; triethylamine; In tert-butyl alcohol; at 50 ℃;

DOI:10.3184/174751912X13352834523329

Reference yield:

methyl deoxycholate (3245-38-3) → C45H56N6O6 (1004519-75-8)

Guidance literature:

Multi-step reaction with 3 steps

1: pyridine; triethylamine / chloroform / 60 °C

2: sodium azide / N,N-dimethyl-formamide / 12 h / 60 °C

3: copper(l) iodide; triethylamine / tert-butyl alcohol / 50 °C

With pyridine; copper(l) iodide; sodium azide; triethylamine; In chloroform; N,N-dimethyl-formamide; tert-butyl alcohol;

DOI:10.3184/174751912X13352834523329

Reference yield:

Deoxycholic acid (83-44-3) → C45H56N6O6 (1004519-75-8)

Guidance literature:

Multi-step reaction with 4 steps

1: acetyl chloride / Cooling with ice

2: pyridine; triethylamine / chloroform / 60 °C

3: sodium azide / N,N-dimethyl-formamide / 12 h / 60 °C

4: copper(l) iodide; triethylamine / tert-butyl alcohol / 50 °C

With pyridine; copper(l) iodide; sodium azide; triethylamine; acetyl chloride; In chloroform; N,N-dimethyl-formamide; tert-butyl alcohol;

DOI:10.3184/174751912X13352834523329

upstream raw materials:

methyl 3,7,12-trideoxy-3α,12α-bis(2-azidoacetyloxy)cholate

phenylacetylene

Deoxycholic acid

methyl deoxycholate