(3S)-3-{2-[5-(2-tert-butyl-benzyl)-3-methyl-6-oxo-6H-pyridazin-1-yl]-propionylamino}-4-oxo-5-(2,3,5,6-tetrafluoro-phenoxy)-pentanoic acid tert-butyl ester

Base Information

• Chemical Name: (3S)-3-{2-[5-(2-tert-butyl-benzyl)-3-methyl-6-oxo-6H-pyridazin-1-yl]-propionylamino}-4-oxo-5-(2,3,5,6-tetrafluoro-phenoxy)-pentanoic acid tert-butyl ester
• CAS No.: 1025154-85-1
• Molecular Formula: C₃₄H₃₉F₄N₃O₆
• Molecular Weight: 661.694

Synonyms:(3S)-3-{2-[5-(2-tert-butyl-benzyl)-3-methyl-6-oxo-6H-pyridazin-1-yl]-propionylamino}-4-oxo-5-(2,3,5,6-tetrafluoro-phenoxy)-pentanoic acid tert-butyl ester

Chemical Property of (3S)-3-{2-[5-(2-tert-butyl-benzyl)-3-methyl-6-oxo-6H-pyridazin-1-yl]-propionylamino}-4-oxo-5-(2,3,5,6-tetrafluoro-phenoxy)-pentanoic acid tert-butyl ester

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Technology Process of (3S)-3-{2-[5-(2-tert-butyl-benzyl)-3-methyl-6-oxo-6H-pyridazin-1-yl]-propionylamino}-4-oxo-5-(2,3,5,6-tetrafluoro-phenoxy)-pentanoic acid tert-butyl ester

There total 1 articles about (3S)-3-{2-[5-(2-tert-butyl-benzyl)-3-methyl-6-oxo-6H-pyridazin-1-yl]-propionylamino}-4-oxo-5-(2,3,5,6-tetrafluoro-phenoxy)-pentanoic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C34H41F4N3O6 (1025154-83-9) → (3S)-3-{2-[5-(2-tert-butyl-benzyl)-3-methyl-6-oxo-6H-pyridazin-1-yl]-propionylamino}-4-oxo-5-(2,3,5,6-tetrafluoro-phenoxy)-pentanoic acid tert-butyl ester (1025154-85-1)

Guidance literature:

With Dess-Martin periodane; In dichloromethane; at 20 ℃; for 1h;

Reference yield: 84.0%

(3S)-3-{2-[5-(2-tert-butyl-benzyl)-3-methyl-6-oxo-6H-pyridazin-1-yl]-propionylamino}-4-oxo-5-(2,3,5,6-tetrafluoro-phenoxy)-pentanoic acid tert-butyl ester (1025154-85-1) → (3S)-3-{2-[5-(2-tert-butyl-benzyl)-3-methyl-6-oxo-6H-pyridazin-1-yl]-propionylamino}-4-oxo-5-(2,3,5,6-tetrafluoro-phenoxy)-pentanoic acid (1025154-48-6)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃; for 1h;

Reference yield:

(3S)-3-{2-[5-(2-tert-butyl-benzyl)-3-methyl-6-oxo-6H-pyridazin-1-yl]-propionylamino}-4-oxo-5-(2,3,5,6-tetrafluoro-phenoxy)-pentanoic acid tert-butyl ester (1025154-85-1) → (S)-3-{2-[5-(2-tert-butyl-benzyl)-3-methyl-6-oxo-6H-pyridazin-1-yl]-propionylamino}-4-oxo-5-(2,3,5,6-tetrafluoro-phenoxy)-pentanoic acid

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃; for 1h;

upstream raw materials:

C₃₄H₄₁F₄N₃O₆

Downstream raw materials:

(3S)-3-{2-[5-(2-tert-butyl-benzyl)-3-methyl-6-oxo-6H-pyridazin-1-yl]-propionylamino}-4-oxo-5-(2,3,5,6-tetrafluoro-phenoxy)-pentanoic acid

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