2-acetyl-N-phenyl-2-(prop-2-ynyl)pent-4-ynamide

Base Information

Chemical Name:2-acetyl-N-phenyl-2-(prop-2-ynyl)pent-4-ynamide
CAS No.:1141891-26-0
Molecular Formula:C₁₆H₁₅NO₂
Molecular Weight:253.301
Hs Code.:

Synonyms:2-acetyl-N-phenyl-2-(prop-2-ynyl)pent-4-ynamide

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Chemical Property of 2-acetyl-N-phenyl-2-(prop-2-ynyl)pent-4-ynamide

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Technology Process of 2-acetyl-N-phenyl-2-(prop-2-ynyl)pent-4-ynamide

There total 1 articles about 2-acetyl-N-phenyl-2-(prop-2-ynyl)pent-4-ynamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 102-01-2,98624-45-4
N-phenylacetoacetamide

: 106-96-7
propargyl bromide

: 1141891-26-0
2-acetyl-N-phenyl-2-(prop-2-ynyl)pent-4-ynamide

Guidance literature:: N-phenylacetoacetamide; With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

propargyl bromide; In N,N-dimethyl-formamide; at 20 ℃; for 4h;
DOI:10.1002/chem.200802304

Reference yield: 87.0%

: 1141891-26-0
2-acetyl-N-phenyl-2-(prop-2-ynyl)pent-4-ynamide

: C₁₆H₁₆N₄O₂

Guidance literature:: With trimethylsilylazide; water; silver carbonate; In dimethyl sulfoxide; at 80 ℃;
DOI:10.1021/acs.orglett.5b00784

Reference yield: 87.0%

: 1141891-26-0
2-acetyl-N-phenyl-2-(prop-2-ynyl)pent-4-ynamide

: 185990-03-8
dimethylphenyl(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)silane

: C₃₀H₃₈BNO₄Si

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In tetrahydrofuran; at 50 ℃; for 6h; Inert atmosphere;
DOI:10.1039/c8cc00097b