ethyl (2E)-2-methyl-3-[1,3-dimethyl-2-(triphenylsiloxy)-4-iodo-3-cyclopentenyl]propenoate

Base Information

Chemical Name:ethyl (2E)-2-methyl-3-[1,3-dimethyl-2-(triphenylsiloxy)-4-iodo-3-cyclopentenyl]propenoate
CAS No.:637740-81-9
Molecular Formula:C₃₁H₃₃IO₃Si
Molecular Weight:608.591
Hs Code.:

Synonyms:ethyl (2E)-2-methyl-3-[1,3-dimethyl-2-(triphenylsiloxy)-4-iodo-3-cyclopentenyl]propenoate

Suppliers and Price of ethyl (2E)-2-methyl-3-[1,3-dimethyl-2-(triphenylsiloxy)-4-iodo-3-cyclopentenyl]propenoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl (2E)-2-methyl-3-[1,3-dimethyl-2-(triphenylsiloxy)-4-iodo-3-cyclopentenyl]propenoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl (2E)-2-methyl-3-[1,3-dimethyl-2-(triphenylsiloxy)-4-iodo-3-cyclopentenyl]propenoate

There total 5 articles about ethyl (2E)-2-methyl-3-[1,3-dimethyl-2-(triphenylsiloxy)-4-iodo-3-cyclopentenyl]propenoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 637741-35-6
2-hydroxy-4-iodo-1,3-dimethyl-cyclopent-3-enecarboxylic acid ethyl ester

: 637740-81-9
ethyl (2E)-2-methyl-3-[1,3-dimethyl-2-(triphenylsiloxy)-4-iodo-3-cyclopentenyl]propenoate

Guidance literature:: Multi-step reaction with 4 steps

1: 100 percent / imidazole / dimethylformamide / 2 h / 20 °C

2: diisobutylaluminum hydride / CH₂Cl₂; hexane / 0.5 h / -78 °C

3: oxalyl chloride; triethylamine; DMSO / CH₂Cl₂ / 1 h / 0 °C

4: 1.02 g / toluene / 72 h / Heating

With 1H-imidazole; oxalyl dichloride; diisobutylaluminium hydride; dimethyl sulfoxide; triethylamine; In hexane; dichloromethane; N,N-dimethyl-formamide; toluene; 3: Swern oxidation / 4: Wittig reaction;
DOI:10.1039/b305818b

Reference yield:

: 637740-80-8
ethyl 1,3-dimethyl-2-oxo-4-iodo-3-cyclopentene-1-carbonate

: 637740-81-9
ethyl (2E)-2-methyl-3-[1,3-dimethyl-2-(triphenylsiloxy)-4-iodo-3-cyclopentenyl]propenoate

Guidance literature:: Multi-step reaction with 5 steps

1: 70 percent / NaBH₄ / methanol / 0.33 h / 0 °C

2: 100 percent / imidazole / dimethylformamide / 2 h / 20 °C

3: diisobutylaluminum hydride / CH₂Cl₂; hexane / 0.5 h / -78 °C

4: oxalyl chloride; triethylamine; DMSO / CH₂Cl₂ / 1 h / 0 °C

5: 1.02 g / toluene / 72 h / Heating

With 1H-imidazole; sodium tetrahydroborate; oxalyl dichloride; diisobutylaluminium hydride; dimethyl sulfoxide; triethylamine; In methanol; hexane; dichloromethane; N,N-dimethyl-formamide; toluene; 4: Swern oxidation / 5: Wittig reaction;
DOI:10.1039/b305818b

Reference yield:

: (4-iodo-1,3-dimethyl-2-triphenylsilanyloxy-cyclopent-3-enyl)-methanol

: 637740-81-9
ethyl (2E)-2-methyl-3-[1,3-dimethyl-2-(triphenylsiloxy)-4-iodo-3-cyclopentenyl]propenoate

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl chloride; triethylamine; DMSO / CH₂Cl₂ / 1 h / 0 °C

2: 1.02 g / toluene / 72 h / Heating

With oxalyl dichloride; dimethyl sulfoxide; triethylamine; In dichloromethane; toluene; 1: Swern oxidation / 2: Wittig reaction;
DOI:10.1039/b305818b