1-(4-methylphenyl)vinylphosphonic acid diethyl ester

Base Information

• Chemical Name: 1-(4-methylphenyl)vinylphosphonic acid diethyl ester
• CAS No.: 1159205-37-4
• Molecular Formula: C₁₃H₁₉O₃P
• Molecular Weight: 254.266
• Mol file: 1159205-37-4.mol

Synonyms:1-(4-methylphenyl)vinylphosphonic acid diethyl ester

Chemical Property of 1-(4-methylphenyl)vinylphosphonic acid diethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(4-methylphenyl)vinylphosphonic acid diethyl ester

There total 9 articles about 1-(4-methylphenyl)vinylphosphonic acid diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

diethyl 1-[(4-methylbenzenesulfonyl)oxy]ethene-alpha-phosphonate (1309980-37-7) + 4-methylphenylboronic acid (5720-05-8) → 1-(4-methylphenyl)vinylphosphonic acid diethyl ester (1159205-37-4)

Guidance literature:

With palladium diacetate; caesium carbonate; In toluene; at 20 ℃;

DOI:10.1021/ol503518h

Reference yield: 99.0%

4-methylphenylboronic acid (5720-05-8) + 1,1,2,2,3,3,4,4,4-nonafluoro-butane-1-sulfonic acid 1-(diethoxy-phosphoryl)-vinyl ester (243137-79-3) → 1-(4-methylphenyl)vinylphosphonic acid diethyl ester (1159205-37-4)

Guidance literature:

With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; caesium carbonate; In toluene; at 20 ℃; Inert atmosphere; Schlenk technique;

DOI:10.1002/cjoc.201500414

Reference yield: 87.0%

nitromethane (75-52-5) + 4-methyl-benzaldehyde (104-87-0) + triethyl phosphite (122-52-1) → 1-(4-methylphenyl)vinylphosphonic acid diethyl ester (1159205-37-4)

Guidance literature:

With 5-hydroxypentylammonium acetate; at 20 ℃; for 2h;

DOI:10.1055/s-0032-1317965

upstream raw materials:

orthoformic acid triethyl ester

1-(4-methylphenyl)ethenylphosphonic acid

(E)-2-(4-methylphenyl)-1-nitroethene

triethyl phosphite

Downstream raw materials:

diethyl 1-(4-methylphenyl)ethylphosphonate

1-(4-methylphenyl)ethylphosphonic acid diethyl ester

1-(4-methylphenyl)ethenyl phosphonic acid monoethyl ester