7-Ethylcamptothecin

Base Information

Chemical Name:7-Ethylcamptothecin
CAS No.:78287-27-1
Molecular Formula:C22H20N2O4
Molecular Weight:376.412
Hs Code.:29349990
European Community (EC) Number:680-163-8
UNII:LPY7FE51IW
DSSTox Substance ID:DTXSID60228960
Nikkaji Number:J448.356A
Wikipedia:SN-22
Wikidata:Q72473443
Mol file:78287-27-1.mol

Synonyms:7-ethylcamptothecin;SN 22;SN-22

Suppliers and Price of 7-Ethylcamptothecin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
7-EthylCamptothecin
10mg
$ 130.00

TCI Chemical
7-Ethylcamptothecin >96.0%(HPLC)
100mg
$ 30.00

TCI Chemical
7-Ethylcamptothecin >96.0%(HPLC)
1g
$ 176.00

DC Chemicals
7-Ethylcamptothecin >98%
20 mg
$ 280.00

Crysdot
7-Ethylcamptothecin 97%
250mg
$ 133.00

ChemScene
7-Ethylcamptothecin 99.58%
5g
$ 366.00

ChemScene
7-Ethylcamptothecin 99.58%
1g
$ 102.00

Chem-Impex
7-Ethylcamptothecin,99%(HPLC) 99%(HPLC)
250MG
$ 39.20

Chem-Impex
7-Ethylcamptothecin,99%(HPLC) 99%(HPLC)
10G
$ 756.00

Chem-Impex
7-Ethylcamptothecin,99%(HPLC) 99%(HPLC)
5G
$ 392.00

Total 120 raw suppliers

Chemical Property of 7-Ethylcamptothecin

Chemical Property:

Appearance/Colour:light pink solid
Vapor Pressure:8.15E-24mmHg at 25°C
Melting Point:236-241oC
Refractive Index:1.712
Boiling Point:752.867 °C at 760 mmHg
PKA:11.24±0.20(Predicted)
Flash Point:409.119 °C
PSA：81.42000
Density:1.436 g/cm³
LogP:2.64200
Storage Temp.:-20°C Freezer
Solubility.:Chloroform and Methanol Mixture (Slightly, Heated, Sonicated), DMSO (Slightly, H
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:376.14230712
Heavy Atom Count:28
Complexity:787

Purity/Quality:

99% ^*data from raw suppliers

7-EthylCamptothecin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 23/34/35
Safety Statements: 3/14-6-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)C4(CC)O)C2=NC5=CC=CC=C51
Isomeric SMILES:CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)O)C2=NC5=CC=CC=C51
Uses An anticancer drug, showed strong activity against various murine tumors. A Camptothecin (CPT) derivative as antineoplastic agent against drug-resistant tumors. Irinotecan USP Related Compound E. An anticancer drug, showed strong activity against various murine tumors. A Camptothecin (CPT) derivative as antineoplastic agent against drug-resistant tumors.

Technology Process of 7-Ethylcamptothecin

There total 17 articles about 7-Ethylcamptothecin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.4%

: 123-38-6
propionaldehyde

: 7689-03-4,91926-09-9
camptothecin

: 78287-27-1
7-ethylcamptothecin

Guidance literature:: With sulfuric acid; dihydrogen peroxide; acetic acid; at -5 - 5 ℃; for 0.166667h; Temperature;

Reference yield: 83.3%

: 3425-61-4
tert-amyl hydroperoxide

: 7689-03-4,91926-09-9
camptothecin

: 78287-27-1
7-ethylcamptothecin

Guidance literature:: With sulfuric acid; iron(II) sulfate; acetic acid; In water; at 0 ℃; for 0.5h;
DOI:10.1080/00397910601038723

Reference yield: 60.0%

: 4433-63-0
Ethyl boronic acid

: 7689-03-4,91926-09-9
camptothecin

: 78287-27-1
7-ethylcamptothecin

Guidance literature:: With tris(2,2'-bipyridyl)ruthenium dichloride; 1-acetoxy-1,2-benziodoxol-3-one; at 30 ℃; for 48h; Inert atmosphere; Irradiation;
DOI:10.1039/c6sc02653b